- Talk to your doctor before using digoxin together with quiNIDine. Combining these medications may significantly increase the blood levels and effects of digoxin.www.drugs.com/drug-interactions/digoxin-with-quinidine-883-0-1981-0.html
Digoxin and quinidine Interactions Checker - Drugs.com
- This report displays the potential drug interactions for the following 2 drugs:
- •digoxin
- •quinidine
- Edit list (add/remove drugs) See more
- Applies to: quinidine and digoxin
- Talk to your doctor before using digoxin together with quiNIDi… See more
- Applies to: digoxin
- Information for this minor interaction is available on the profe… See more
Quinidine and digoxin. An important interaction - PubMed
On average, the serum digoxin doubles during treatment with therapeutic doses of quinidine. Almost every patient treated with quinidine will have a decrease in the renal clearance of …
- Author: J T Bigger, J T Bigger, E B Leahey, E B Leahey
- Publish Year: 1982
- bing.com › videosWatch full videoWatch full video
The Quinidine-Digoxin Interaction — What Do We Know about It?
In 1978, three groups independently described a drug interaction between quinidine and digoxin: When quinidine is given to patients taking digoxin, the serum digoxin concentration increases. …
- Author: J.Thomas Bigger, J.Thomas Bigger
- Publish Year: 1981
Drug Interactions with Digoxin: The Role of P-glycoprotein
Oct 1, 2004 · One of the most widely studied drug interactions is the interaction between digoxin and quinidine. Patients who receive the combination almost always will have a significant …
Quinidine-Digoxin Interaction - The New England …
Unlike other investigations, our studies provided no evidence that quinidine displaced digoxin at specific cardiac binding sites. The elevated digoxin levels …
- Author: Powell, Fenster Pe, Hager Wd, Graves P, Wandell M, Conrad K
- Publish Year: 1980
Inhibition of P-Glycoprotein–Mediated Drug Transport
Feb 2, 1999 · If P-glycoprotein is an important factor in the digoxin-quinidine interaction in vivo, quinidine should alter digoxin disposition in mdr1a(+/+) mice, elevating digoxin concentrations in plasma (and perhaps other sites), but little …
- People also ask
In this study, we determined the time course of elevation serum digoxin concentration after institution of quinidine therapy in a group of patients with arrhythmias. We also determined the …
The Quinidine-Digoxin Interaction in Perspective | Clinical ...
Dec 13, 2012 · The administration of quinidine to patients receiving digoxin maintenance therapy results in a marked increase in the serum/plasma digoxin concentration. With over 90% of …
Quinidine-digoxin interaction: time course and pharmacokinetics
In group II (large dose), quinidine reduced digoxin total clearance by 36 percent, renal clearance by 54 percent and nonrenal clearance by 22 percent. The reduction in digoxin volume of …
Quinidine and digoxin. An important interaction. - DrugBank Online
On average, the serum digoxin doubles during treatment with therapeutic doses of quinidine. Almost every patient treated with quinidine will have a decrease in the renal clearance of …
Related searches for Quinidine Digoxin
Skip to content