Aptamer Details

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Aptamer-6 (ID# 7227)

Aptamer Chemistry: DNA Target: S/RBD receptor binding Antigen/Target Category: Protein Affinity (Kd): 27.6 nM (reported value) Binding Conditions/Buffer: n Dulbecco's phosphate-buffered saline (DPBS) containing 1 mM MgCl2 (DPBS/Mg) Binding Temp: 23°C°C Refolding Protocol: mFold Specificity: highly specific Comments: Binds to the receptor-binding domain (RBD) of COVID-19 virus and inhibits the S/RBD interaction between virus and host cell.

Sequence (): 5'dApdTpdCpdTpdApdGpdApdGpdTpdGpdApdCpdGpdCpdApdGpdCpdApdGpdGpdGpdCpdTpdTpdGpdGpdGpdTpdTpdGpdGpdGpdApdApdTpdApdApdApdGpdApdTpdGpdTpdGpdGpdGpdApdGpdGpdCpdGpdGpdCpdGpdApdApdCpdApdTpdGpdGpdApdCpdApdCpdGpdGpdTpdGpdGpdCpdTpdTpdApdGpdTp3' Length: 76 Molecular Weight: 23902.47 g/mole Extinction Coefficient: 1294263 L/(mole·cm) GC Content: 55.26% nmoles/OD₂₆₀: 0.77 μg/OD₂₆₀: 18.47

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

https://doi.org/10.1002/anie.202100345

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Aptamer Details

Aptamer-6 (ID# 7227)

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