A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma
A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma
2010
Gail Rogers
Darren Warburton
Thomas Mariani
Sunita Sharma
Stephen Leeder
Gail Bartlett
Vincent Carey
Abstract
Abstract Rationale: Animal models demonstrate that aberrant gene expression in utero can result in abnormal pulmonary phenotypes. Objectives: We sought to identify genes that are differentially expressed during in utero airway development and test the hypothesis that variants in these genes influence lung function in patients with asthma.
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