Bicyclic and tetracyclic diterpenes from a Trichoderma symbiont of Taxus baccata
Bicyclic and tetracyclic diterpenes from a Trichoderma symbiont of Taxus baccata
Phytochemistry, 2014
Mercedes Bonfill
Abstract
Trichoderma atroviridae UB-LMA is an endophytic fungus isolated from Taxus baccata trees. Liquid-state fermentation coupled to in situ solid phase extraction (SPE) was applied, and four compounds were discovered. Compounds 2-4 belong to the harziane tetracyclic diterpene family. Bicylic compound 1 may represent the biosynthetic precursor of this scarce family of compounds.
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