DNA & Genealogy PowerPoint

2015

Nature Reviews Genetics, 2004

Public demand and the development of large public and private databases of genetic information across human populations has encouraged the development of the new and rapidly growing field of genetic ancestry testing. Both the promise of the science that underlies this field and a lack of a full understanding of its limitations have fuelled the increased public interest in genetic

this book is an introduction to forensic genetic . from collecting samples to DNA typing

Trends in genetics : TIG, 2009

Annals of Human Genetics, 2003

The goal of this Y-DNA research study is to utilize traditional genealogical methods and current DNA methods and technology to identify the unique Y-DNA genetic signature of John Hart, the thirteenth signer of the Declaration of Independence, and an American Founding Father. Traditional genealogical methods provided the foundation for our study. We researched the history and genealogy of the family of John Hart, and we identified and located six pedigreed descendants of his patrilineal lineage, including four son-after-son descendants of three of his sons, and two son-after-son descendants of his paternal uncle. We then utilized genetic genealogical methods to compare the Y-DNA genetic profiles of these six pedigreed descendants. We determined that they all genetically matched each other at both 37 and 67 STR markers. Their lineage-specific haplotype was unique to the point that they had no other genetic matches at 67 STR markers, other than their fellow pedigreed Hart descendants. Based on the results of SNP genotyping through FTDNA’s “Big Y” test, we established their haplogroup/subclade designation, which, in conjunction with their lineage-specific haplotype, comprises the Y-DNA genetic signature of their patrilineal line, back to their most recent common ancestor, the grandfather of John Hart the Signer. This report of the Y-DNA genetic signature of one of America’s Founding Fathers proves historic lines of descent using genealogical research methods, establishes a Y-DNA genetic signature that can be utilized to identify previously unknown or unrecognized descendants, and demonstrates a pioneering methodology that can be applied to studies of other historical figures and their descendants. Revised November 23, 2018

Nature Reviews Genetics, 2004

Cite as: Hössjer O, Gauger A, Reeves C (2016) Genetic modeling of human history part 1: comparison of common descent and unique origin approaches. BIO-Complexity 2016 (3):1–15.