Smiles or SMILES may refer to:

See also

The simplified molecular-input line-entry system (SMILES) is a specification in form of a line notation for describing the structure of chemical species using short ASCII strings. SMILES strings can be imported by most molecule editors for conversion back into two-dimensional drawings or three-dimensional models of the molecules.

The original SMILES specification was initiated by David Weininger at the USEPA Mid-Continent Ecology Division Laboratory in Duluth in the 1980s. Acknowledged for their parts in the early development were "Gilman Veith and Rose Russo (USEPA) and Albert Leo and Corwin Hansch (Pomona College) for supporting the work, and Arthur Weininger (Pomona; Daylight CIS) and Jeremy Scofield (Cedar River Software, Renton, WA) for assistance in programming the system." The Environmental Protection Agency funded the initial project to develop SMILES.

It has since been modified and extended by others, most notably by Daylight Chemical Information Systems. In 2007, an open standard called "OpenSMILES" was developed by the Blue Obelisk open-source chemistry community. Other 'linear' notations include the Wiswesser Line Notation (WLN), ROSDAL and SLN (Tripos Inc).

Lonely may refer to:

See also

"Lonely" is the second single by South Korean girl group 2NE1 from their 2011 extended play, 2NE1. Later that year, a Japanese version of the song was released and was included on their first Japanese EP Nolza. A short version of the music video was uploaded through 2NE1's official YouTube account.

Background

The song was written and produced by Teddy Park. According to the CEO of YG Entertainment, Yang Hyun Suk, "2NE1’s new song counter feeds the people with an analogue sound unlike the majority who used strong electronics and house music and maybe that is why Will I. Am have [sic] found it interesting". They also released teasers of "Lonely" starting with CL and Minzy on May 9, and Dara and Bom on May 10. The music video was released on May 11, 2011.

Chart performance

By the end of 2011, "Lonely" was downloaded 2,935,930 times, and reached the fourteenth position in the 2011 Gaon Year-End Chart, becoming the third-highest charting of 2NE1's 2011 singles.

Music video

The music video for "Lonely" was filmed April 27, 2011, directed by Han Samin, who directed the music video for Big Bang's fourth mini-special album's title song, "Love Song". The video was posted on their YouTube account on May 11, 2011.

"Lonely" is a pop song written by Merril Bainbridge and Owen Bolwell, produced by Siew for Bainbridge's second album Between the Days (1998). It was released as the album's first single in Australia in April 1998 and the United States and Japan in August 1998 (see 1998 in music) as a CD single. The bridge of the song samples the lyrics from the nursery rhyme "Georgie Porgie".

The song made its debut to the Australian ARIA Singles Chart at number seventy-four, making the song Bainbridge's fifth song to reach the top one hundred. On its second week it fell three places to seventy-seven but by the next week the song jumped nine places to sixty-eight and after six weeks of being in the chart it broke the top fifty at number forty-eight. After two weeks of being in the top fifty the song peaked at its peak position in Australia at number forty, then dropping out of the top fifty the next week. The song spent a total of three weeks in the top fifty and seventeen weeks in the top one hundred.

Sick may refer to:

Music

Albums

Songs

Other media

People with the surname

Sick: The Life and Death of Bob Flanagan, Supermasochist is a 1997 documentary film directed by Kirby Dick about Bob Flanagan, a Los Angeles writer, poet, performance artist, comic, and BDSM celebrity, who suffered from and later died of cystic fibrosis. The film premiered at the 1997 Sundance Film Festival, where it was awarded a Special Jury Prize.

Synopsis

The film chronicles Flanagan for several years leading up to his death in 1996. It explores various aspects of his life, artwork, and philosophy through interviews and other personal footage depicting Flanagan, his partner Sheree Rose, and the Flanagan family. Sick also features Flanagan's home movies, performance videos, and video diaries, as well as an excerpt of Flanagan's performance in the music video for "Happiness in Slavery" by Nine Inch Nails.

In the film, Flanagan explains his use of BDSM for sexual gratification and also as a therapeutic device to regain control over his body from cystic fibrosis. He discusses his conceptual, performance, and video art, which often relates to pain, illness, medicine, and sexuality. Flanagan also serves as a camp counselor for children with cystic fibrosis and meets with a young woman who suffers from cystic fibrosis and who visits him under the auspices of the Make-A-Wish Foundation.