Afternoon is that time of day from 1:00 PM and 5:00 PM.

Afternoon may also refer to:

Monthly Afternoon (月刊アフタヌーン, Gekkan Afutanūn) is a Japanese monthly seinen manga anthology published by Kodansha under the Afternoon line of magazines. The first issue was released with a cover date of January 25, 1986. Each issue typically has around thirty ongoing stories by various authors and runs about 800 pages. Afternoon has spawned many successful seinen manga series such as Oh My Goddess!, Genshiken, Blade of the Immortal and Big Windup! It is part of Kodansha's "1day" series, which also includes the magazines Morning and Evening. In its October 2008 issue, a spin-off magazine called good! Afternoon was announced to be launched.

Manga artists and series featured in Afternoon

MID or Mid may refer to:

Computers and electronics

Medicine and biology

Military

Midline-1 is a protein that in humans is encoded by the MID1 gene.

Function

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing; however, the full length nature of two variants has not been determined.

Midline-2 is a protein that in humans is encoded by the MID2 gene.

Function

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Its function has not been identified. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Interactions

MID2 has been shown to interact with MID1.

References

Further reading

Wildwood, also known as the General Alfred Beckley Home, is a historic home located at Beckley, Raleigh County, West Virginia. The house is open as the Wildwood House Museum and was listed on the National Register of Historic Places in 1970.

History

General Alfred Beckley (1802–88) wanted his home to be the center of what he envisioned for Beckley, West Virginia which he founded in 1838. Although his town was a piece of paper in 1838, it would later become the county seat of Raleigh County, West Virginia, which was also founded by Beckley in 1850. His house was built in 1835-36, initially as an unpretentious double log cabin. "I took possession of a double log cabin built for me in the fall of 1835 by Mr. John Lilly Sr. of Bluestone.." Originally, the residence was named Park Place. According to Alfred Beckley, "I changed the name of my residence from 'Park Place', a name given it by my kinsman, Clarkson Prince to that of 'Wildwood'".

Description

The current appearance of Wildwood began in 1874 with remodeling by Alfred Beckley. This included the addition of a kitchen and dining room to the back of the house. The log cabins exterior was also covered in white clapboard. This was replaced in the 1970s with aluminum siding. Most of the original pine floor exists, and wood beams have been exposed within parts of the house to demonstrate its log cabin origins. There have been plans to restore the structure to its original 1874 appearance.

Winter is the coldest season of the year in polar and temperate climates, between autumn and spring. Winter is caused by the axis of the Earth in that hemisphere being oriented away from the Sun. Different cultures define different dates as the start of winter, and some use a definition based on weather. When it is winter in the Northern Hemisphere, it is summer in the Southern Hemisphere, and vice versa. In many regions, winter is associated with snow and freezing temperatures. The moment of winter solstice is when the sun's elevation with respect to the North or South Pole is at its most negative value (that is, the sun is at its farthest below the horizon as measured from the pole), meaning this day will have the shortest day and the longest night. The earliest sunset and latest sunrise dates outside the polar regions differ from the date of the winter solstice, however, and these depend on latitude, due to the variation in the solar day throughout the year caused by the Earth's elliptical orbit (see earliest and latest sunrise and sunset).