Otterbein University is a private, four-year liberal arts college in Westerville, Ohio, United States. It offers 74 majors and 44 minors, as well as 8 graduate programs. Featured programs include engineering, business management, education, and music, as well as programs and pre-professional advising that prepare students for study in law and medicine.

The University was founded in 1847 by the Church of the United Brethren in Christ. As a result of a division and two mergers involving the Church, the University has since 1968 been associated with the United Methodist Church. The University is named for United Brethren founder the Rev. Philip William Otterbein. In its 2012 edition of America's Best Colleges, Otterbein was ranked 14th in the "Regional Universities (Midwest)" category by U.S. News & World Report. In 2010, its name reverted from Otterbein College to Otterbein University to reflect the increasing array of graduate and undergraduate programs offered.

It is notably an undergraduate institution (with 2700 students), and 400 graduate students on the campus. Otterbein has over 100 student organizations and a popular Greek presence. The school's mascot is Cardy the Cardinal and the school is a member of the Ohio Athletic Conference in Division III athletics.