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Galactoside 2-alpha-L-fucosyltransferase 2 is an enzyme that in humans is encoded by the FUT2gene.[5][6] It affects the secretor status of ABO antigens.[7]
Approximately 20% of Caucasians are non-secretors due to the G428A (rs601338) and C571T (rs492602?) nonsense mutations in FUT2 and therefore have strong although not absolute protection from the norovirus GII.4.[citation needed]
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^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Ball SP, Tongue N, Gibaud A, Le Pendu J, Mollicone R, Gerard G, Oriol R (Feb 1992). "The human chromosome 19 linkage group FUT1 (H), FUT2 (SE), LE, LU, PEPD, C3, APOC2, D19S7 and D19S9". Ann Hum Genet. 55 (Pt 3): 225–33. doi:10.1111/j.1469-1809.1991.tb00417.x. PMID1763885. S2CID30777695.
Reguigne-Arnould I; Couillin P; Mollicone R; et al. (1995). "Relative positions of two clusters of human alpha-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19". Cytogenet. Cell Genet. 71 (2): 158–62. doi:10.1159/000134098. PMID7656588.
Koda Y; Soejima M; Johnson PH; et al. (1997). "Missense mutation of FUT1 and deletion of FUT2 are responsible for Indian Bombay phenotype of ABO blood group system". Biochem. Biophys. Res. Commun. 238 (1): 21–5. doi:10.1006/bbrc.1997.7232. PMID9299444.
Liu Y; Koda Y; Soejima M; et al. (1998). "Extensive polymorphism of the FUT2 gene in an African (Xhosa) population of South Africa". Hum. Genet. 103 (2): 204–10. doi:10.1007/s004390050808. PMID9760207. S2CID25253767.
Lindesmith L; Moe C; Marionneau S; et al. (2003). "Human susceptibility and resistance to Norwalk virus infection". Nat. Med. 9 (5): 548–53. doi:10.1038/nm860. PMID12692541. S2CID28663420.
Guo ZH; Xiang D; Zhu ZY; et al. (2004). "[Analysis on FUT1 and FUT2 gene of 10 para-Bombay individuals in China]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 21 (5): 417–21. PMID15476160.
Chen DP; Tseng CP; Wang WT; et al. (2005). "Two prevalent h alleles in para-Bombay haplotypes among 250,000 Taiwanese". Ann. Clin. Lab. Sci. 34 (3): 314–8. PMID15487706.
Pang H, Soejima M, Koda Y, Kimura H (2005). "A novel tetrameric short tandem repeat located in the 3' flanking region of the human ABO-secretor gene (FUT2) and association between FUT2 and FUT2/01 loci". Hum. Biol. 76 (5): 789–95. doi:10.1353/hub.2005.0008. PMID15757249. S2CID1201579.
