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Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
AP-4 complex subunit mu-1 is a protein that in humans is encoded by the AP4M1gene.[5][6][7]
Function
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.[7]
The AP4-complex-mediated trafficking plays a crucial role in brain development and functioning.[9] Mutations of the gene cause spastic paraplegia 50, one of the many subtypes of spastic paraplegia.