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Knowledge Extraction of Long-Term Complications from Clinical Narratives of Blood Cancer Patients with HCT Treatments

Published: 15 August 2018 Publication History

Abstract

Interactive information extraction (IE) systems supported by biomedical ontologies are intelligent natural language processing (NLP) tools to understand literature and clinical narratives and discover meaningful domain knowledge from unstructured text. This study developed integrated IE systems to detect treatment complications of blood cancer patients from Electrical Medical Records (EMR) in the Long-Term Follow-Up (LTFU) protocol following Hematopoietic Cell Transplantation (HCT). The performance of the proposed approach was very encouraging compared to the gold-standard datasets manually reviewed by domain experts. In addition, the NLP system identified significant amount of cases not caught by experts.

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W.Z. Zhu, H.Q. Li. 2016. An Ontology-supported OCR Error Correction Platform for Digitized Clinical Narratives Using Crowdsourced Responses, 2016 AIMA Joint Summit on Translational Science.
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H.J. Murff, F. FitzHenry, M.E. Matheny, N. Gentry, K.L. Kotter, K. Crimin, R.S. Dittus, A.K. Rosen, P.L. Elkin, S.H. Brown, T. Speroff. 2011. Automated Identification of Postoperative Complications Within an Electronic Medical Record Using Natural Language Processing. J AmMed Inform Assoc. 2011;306(8):848--855.
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  1. Knowledge Extraction of Long-Term Complications from Clinical Narratives of Blood Cancer Patients with HCT Treatments

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    cover image ACM Conferences
    BCB '18: Proceedings of the 2018 ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics
    August 2018
    727 pages
    ISBN:9781450357944
    DOI:10.1145/3233547
    Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for third-party components of this work must be honored. For all other uses, contact the Owner/Author.

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    Publication History

    Published: 15 August 2018

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    Author Tags

    1. information extraction from electrical medical records
    2. natural language processing
    3. optical character recognition (ocr)
    4. user relevance feedback

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    • the Leukemia & Lymphoma Society Scholar Award for Clinical Research (S Armenian)

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    BCB '18 Paper Acceptance Rate 46 of 148 submissions, 31%;
    Overall Acceptance Rate 254 of 885 submissions, 29%

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