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A Dependability Preserving Fluid-Level Synthesis for Reconfigurable Droplet-Based Microfluidic Biochips

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VLSI Design and Test (VDAT 2017)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 711))

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Abstract

Due to inherent reconfigurable capability, digital microfluidic biochips (DMFBs) have been a prime platform for critical medical diagnosis, real time bioassays, and lab-on-chip experiments. However, dependability is an urgent need to decide the correct outcome from a bioassay execution. To make a DMFB dependable in high frequency applications, a single electrode must not be frequently used as it may result in over-actuation problem. An over-actuated cell degrades over time and results a failure. Current fluid-level synthesis method only considers in minimizing the total completion time of the assay. Besides, recent technologies use abundant re-execution and perform costly online synthesis whenever such a fault is discovered. Two papers address the dependability issue and propose a placement solution. Here, we present a complete fluid-level synthesis to prepare binding, scheduling, placement, and routing solutions for a given bioassay. The concerned problem is proved to be NP-complete. A dynamic programming formulation is followed to obtain a solution in pseudo-polynomial time. Several benchmarks are used to evaluate the proposed method.

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Correspondence to Piyali Datta .

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Chakraborty, A., Datta, P., Dhal, D., Pal, R.K. (2017). A Dependability Preserving Fluid-Level Synthesis for Reconfigurable Droplet-Based Microfluidic Biochips. In: Kaushik, B., Dasgupta, S., Singh, V. (eds) VLSI Design and Test. VDAT 2017. Communications in Computer and Information Science, vol 711. Springer, Singapore. https://doi.org/10.1007/978-981-10-7470-7_65

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  • DOI: https://doi.org/10.1007/978-981-10-7470-7_65

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-7469-1

  • Online ISBN: 978-981-10-7470-7

  • eBook Packages: Computer ScienceComputer Science (R0)

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