Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope IPRRNVATL
Patskovska, L., Patskovsky, Y., Krogsgaard, M.To be published.
7LFZ
Human leukocyte antigen B*07:02 in complex with SARS-CoV2 epitope IPRRNVATL
- PDB DOI: https://doi.org/10.2210/pdb7LFZ/pdb
- Classification: IMMUNE SYSTEM/VIRAL PROTEIN
- Organism(s): Homo sapiens, Severe acute respiratory syndrome coronavirus 2
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2021-01-19 Released: 2021-02-03
- Funding Organization(s): National Institutes of Health/National Cancer Institute (NIH/NCI)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.224
- R-Value Work: 0.181
- R-Value Observed: 0.182
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
| Molecule | Chains | Sequence Length | Organism | Details | Image |
|---|---|---|---|---|---|
| HLA class I histocompatibility antigen, B-7 alpha chain | 275 | Homo sapiens | Mutation(s): 0 Gene Names: HLA-B, HLAB | ||
Find proteins for P01889 (Homo sapiens) Explore P01889 Go to UniProtKB: P01889 | |||||
PHAROS: P01889 GTEx: ENSG00000234745 | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P01889 | ||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
| Molecule | Chains | Sequence Length | Organism | Details | Image |
|---|---|---|---|---|---|
| Beta-2-microglobulin | 100 | Homo sapiens | Mutation(s): 0 Gene Names: B2M, CDABP0092, HDCMA22P | ||
Find proteins for P61769 (Homo sapiens) Explore P61769 Go to UniProtKB: P61769 | |||||
PHAROS: P61769 GTEx: ENSG00000166710 | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P61769 | ||||
| |||||
Find similar proteins by: Sequence | 3D Structure
| Molecule | Chains | Sequence Length | Organism | Details | Image |
|---|---|---|---|---|---|
| ORF1ab | 9 | Severe acute respiratory syndrome coronavirus 2 | Mutation(s): 0 | ||
Find proteins for P0DTD1 (Severe acute respiratory syndrome coronavirus 2) Explore P0DTD1 Go to UniProtKB: P0DTD1 | |||||
| UniProt Group | P0DTD1 | ||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.224
- R-Value Work: 0.181
- R-Value Observed: 0.182
- Space Group: P 41 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 65.636 | α = 90 |
| b = 65.636 | β = 90 |
| c = 237.472 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2021-02-03 Deposition Author(s): Patskovska, L., Patskovsky, Y., Krogsgaard, M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Cancer Institute (NIH/NCI) | United States | CA243486-01A1 |
Revision History (Full details and data files)
- Version 1.0: 2021-02-03
Type: Initial release - Version 1.1: 2023-10-18
Changes: Data collection, Database references, Refinement description - Version 1.2: 2024-10-23
Changes: Structure summary