Defying Expectations: How Neurons Compute Prediction Errors in Visual Cortex

Neuron. 2020 Dec 23;108(6):1016-1019. doi: 10.1016/j.neuron.2020.12.005.

Authors

Affiliations

¹ Centre for Discovery Brain Sciences, School of Biomedical Sciences Edinburgh, Edinburgh EH8 9XD, UK.
² Centre for Discovery Brain Sciences, School of Biomedical Sciences Edinburgh, Edinburgh EH8 9XD, UK; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH8 9XD, UK. Electronic address: n.rochefort@ed.ac.uk.

PMID: 33357416
DOI: 10.1016/j.neuron.2020.12.005

Abstract

In this issue of Neuron, Jordan and Keller (2020) explore subthreshold computations underlying predictive coding using whole-cell recordings in mouse visual cortex. Their findings suggest that layer 2/3, but not layer 5/6, neurons compute prediction errors by subtracting predicted and actual visual flow inputs generated by locomotion.

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MeSH terms

Animals
Locomotion
Mice
Motivation
Neurons
Patch-Clamp Techniques
Visual Cortex*