Nothing Special   »   [go: up one dir, main page]

Hydroxyl-directed stereoselective diboration of alkenes

J Am Chem Soc. 2014 Jul 2;136(26):9264-7. doi: 10.1021/ja504228p. Epub 2014 Jun 24.

Abstract

An alkoxide-catalyzed directed diboration of alkenyl alcohols is described. This reaction occurs in a stereoselective fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrates. After oxidation, the reaction generates 1,2-diols such that the process represents a method for the stereoselective directed dihydroxylation of alkenes.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Alcohols / chemistry
  • Alkenes / chemistry*
  • Boron Compounds / chemical synthesis*
  • Boron Compounds / chemistry
  • Catalysis
  • Hydroxyl Radical
  • Molecular Structure
  • Stereoisomerism

Substances

  • Alcohols
  • Alkenes
  • Boron Compounds
  • Hydroxyl Radical