Abstract
Microbial pathogens cause a spectrum of diseases in humans. Although the disease mechanisms vary considerably, most pathogens have developed virulence factors that interact with host molecules, often usurping normal cellular processes, including cytoskeletal dynamics and vesicle targeting. These virulence factors often mimic host molecules, and mediate events as diverse as bacterial invasion, antiphagocytosis, and intracellular parastism.
MeSH terms
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Animals
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Bacteria / genetics
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Bacterial Adhesion
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Bacterial Infections / microbiology
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Bacterial Infections / pathology
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Bacterial Physiological Phenomena*
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Bacterial Proteins / chemistry
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Bacterial Proteins / genetics
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Bacterial Proteins / physiology
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Cytoskeleton / physiology
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Eukaryotic Cells / microbiology
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Eukaryotic Cells / ultrastructure
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GTP Phosphohydrolases / physiology
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Humans
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Ligands
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Mammals / microbiology
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Molecular Mimicry*
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Phagocytosis
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Receptors, Cell Surface / physiology
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Signal Transduction
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Vacuoles / microbiology
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Virulence
Substances
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Bacterial Proteins
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Ligands
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Receptors, Cell Surface
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GTP Phosphohydrolases