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Tnf tumor necrosis factor [ Dipodomys spectabilis (banner-tailed kangaroo rat) ]

Gene ID: 122111281, updated on 22-Mar-2024

Summary

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Gene symbol
Tnf
Gene description
tumor necrosis factor
Gene type
protein coding
RefSeq status
MODEL
Organism
Dipodomys spectabilis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae; Dipodomyinae; Dipodomys
Orthologs
human mouse all
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Genomic context

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See Tnf in Genome Data Viewer
Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
100 current ASM1905484v1 (GCF_019054845.1) Unplaced Scaffold NW_024870762.1 (5526620..5529459, complement)

NW_024870762.1Genomic Context describing neighboring genes Neighboring gene leukocyte-specific transcript 1 protein-like Neighboring gene lymphotoxin beta Neighboring gene lymphotoxin alpha Neighboring gene NFKB inhibitor like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024870762 Unplaced Scaffold Reference ASM1905484v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD40 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dipodomys spectabilis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1905484v1

Genomic

  1. NW_024870762.1 Reference ASM1905484v1

    Range
    5526620..5529459 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042684007.1 → XP_042539941.1  tumor necrosis factor isoform X3

    Conserved Domains (1) summary
    cd00184
    Location:87 → 229
    TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

  2. XM_042684005.1 → XP_042539939.1  tumor necrosis factor isoform X1

    Conserved Domains (1) summary
    cd00184
    Location:90 → 232
    TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

  3. XM_042684006.1 → XP_042539940.1  tumor necrosis factor isoform X2

    Conserved Domains (1) summary
    cd00184
    Location:90 → 232
    TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
Nucleotide Protein
Heading Accession and Version

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