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TNF tumor necrosis factor [ Suncus etruscus (white-toothed pygmy shrew) ]

Gene ID: 125996221, updated on 22-Mar-2024

Summary

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Gene symbol
TNF
Gene description
tumor necrosis factor
See related
EnsemblRapid:ENSSRTG00000023201
Gene type
protein coding
RefSeq status
MODEL
Organism
Suncus etruscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae; Crocidurinae; Suncus
Orthologs
human mouse all
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Genomic context

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See TNF in Genome Data Viewer
Location:
chromosome: 18
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_02 current mSunEtr1.pri.cur (GCF_024139225.1) 18 NC_064865.1 (34580682..34582467)

Chromosome 18 - NC_064865.1Genomic Context describing neighboring genes Neighboring gene NFKB inhibitor like 1 Neighboring gene lymphotoxin alpha Neighboring gene lymphotoxin beta Neighboring gene natural cytotoxicity triggering receptor 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064865.1 Chromosome 18 Reference mSunEtr1.pri.cur

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD40 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_024139225.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSunEtr1.pri.cur

Genomic

  1. NC_064865.1 Reference mSunEtr1.pri.cur

    Range
    34580682..34582467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049765176.1 → XP_049621133.1  tumor necrosis factor

    Related
    ENSSRTP00000017844.1, ENSSRTT00000029647.1
Nucleotide Protein
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