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Tnf tumor necrosis factor [ Arvicola amphibius (Eurasian water vole) ]

Gene ID: 119822506, updated on 21-Mar-2024

Summary

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Gene symbol
Tnf
Gene description
tumor necrosis factor
See related
EnsemblRapid:ENSAAPG00005023293
Gene type
protein coding
RefSeq status
MODEL
Organism
Arvicola amphibius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Arvicolinae; Arvicola
Orthologs
human mouse all
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Genomic context

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See Tnf in Genome Data Viewer
Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
101 current mArvAmp1.2 (GCF_903992535.2) 9 NC_052055.2 (124338241..124340612, complement)
100 previous assembly mArvAmp1.1 (GCF_903992535.1) 9 NC_052055.1 (124338241..124340612, complement)

Chromosome 9 - NC_052055.2Genomic Context describing neighboring genes Neighboring gene H-2 class I histocompatibility antigen, L-D alpha chain-like Neighboring gene leukocyte specific transcript 1 Neighboring gene NFKB inhibitor like 1 Neighboring gene ATPase H+ transporting V1 subunit G2 Neighboring gene lymphotoxin beta Neighboring gene lymphotoxin alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD40 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Arvicola amphibius Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mArvAmp1.2

Genomic

  1. NC_052055.2 Reference mArvAmp1.2

    Range
    124338241..124340612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038341895.1 → XP_038197823.1  tumor necrosis factor

    Related
    ENSAAPP00005029825.1, ENSAAPT00005032875.1
    Conserved Domains (1) summary
    pfam00229
    Location:105 → 235
    TNF; TNF(tumor Necrosis Factor) family
Nucleotide Protein
Heading Accession and Version

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