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TNF tumor necrosis factor [ Bos mutus (wild yak) ]

Gene ID: 102277911, updated on 10-Mar-2024

Summary

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Gene symbol
TNF
Gene description
tumor necrosis factor
Locus tag
M91_10752
See related
Ensembl:ENSBMUG00000013690
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos mutus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See TNF in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
101 current BosGru_v2.0 (GCF_000298355.1) Unplaced Scaffold NW_005394817.1 (170906..173674)

NW_005394817.1Genomic Context describing neighboring genes Neighboring gene NFKB inhibitor like 1 Neighboring gene lymphotoxin alpha Neighboring gene lymphotoxin beta Neighboring gene leukocyte specific transcript 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005394817.1 Unplaced Scaffold Reference BosGru_v2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yak genome and adaptation to life at high altitude. Qiu Q, et al. Nat Genet, 2012 Jul 1. PMID 22751099
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD40 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos mutus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BosGru_v2.0 Primary Assembly

Genomic

  1. NW_005394817.1 Reference BosGru_v2.0 Primary Assembly

    Range
    170906..173674
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005904178.1 → XP_005904240.1  tumor necrosis factor isoform X1

    See identical proteins and their annotated locations for XP_005904240.1

    UniProtKB/TrEMBL
    L8I119
    Conserved Domains (1) summary
    pfam00229
    Location:103 → 234
    TNF; TNF(tumor Necrosis Factor) family

  2. XM_005904179.2 → XP_005904241.1  tumor necrosis factor isoform X2

    See identical proteins and their annotated locations for XP_005904241.1

    Related
    ENSBMUP00000018087.1, ENSBMUT00000020906.1
    Conserved Domains (1) summary
    pfam00229
    Location:102 → 233
    TNF; TNF(tumor Necrosis Factor) family
Nucleotide Protein
Heading Accession and Version

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