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Tnf tumor necrosis factor [ Jaculus jaculus (lesser Egyptian jerboa) ]

Gene ID: 101614750, updated on 8-Mar-2024

Summary

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Gene symbol
Tnf
Gene description
tumor necrosis factor
Gene type
protein coding
RefSeq status
MODEL
Organism
Jaculus jaculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Dipodoidea; Dipodidae; Dipodinae; Jaculus
Orthologs
human mouse all
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Genomic context

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See Tnf in Genome Data Viewer
Location:
chromosome: 8
Exon count:
4
Annotation release Status Assembly Chr Location
102 current mJacJac1.mat.Y.cur (GCF_020740685.1) 8 NC_059109.1 (374659..376739, complement)
101 previous assembly JacJac1.0 (GCF_000280705.1) Unplaced Scaffold NW_004504492.1 (377017..378686, complement)

Chromosome 8 - NC_059109.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene lymphotoxin beta Neighboring gene lymphotoxin alpha Neighboring gene NFKB inhibitor like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD40 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Jaculus jaculus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mJacJac1.mat.Y.cur Primary Assembly

Genomic

  1. NC_059109.1 Reference mJacJac1.mat.Y.cur Primary Assembly

    Range
    374659..376739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004671882.2 → XP_004671939.1  tumor necrosis factor

    See identical proteins and their annotated locations for XP_004671939.1

    UniProtKB/TrEMBL
    A0A8C5JVT1, A0A8C5KW61
    Conserved Domains (1) summary
    pfam00229
    Location:104 → 234
    TNF; TNF(Tumour Necrosis Factor) family
Nucleotide Protein
Heading Accession and Version

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