Summary: The conventional generalized spatial modulation (GSM) simultaneously activates multiple transmit antennas in order to improve the spectral efficiency of the original SM. In this letter, to lessen the hardware burden of the multiple RF chains, we provide a new scheme that is designed by combining the GSM scheme using only two active antennas with quaternary quasi-orthogonal sequences of a length of two. Compared with the other SM schemes, the proposed scheme has significant benefits in average error performances and/or their hardware complexities of the RF systems.