Vertebrate microRNA genes

LP Lim, ME Glasner, S Yekta, CB Burge, DP Bartel - Science, 2003 - science.org
MicroRNAs (miRNAs) are an abundant class of 22-nucleotide (nt) noncoding RNAs, some
of which are known to control the expression of other genes at the posttranscriptional level (1–…

A uniform system for the annotation of vertebrate microRNA genes and the evolution of the human microRNAome

B Fromm, T Billipp, LE Peck, M Johansen… - Annual review of …, 2015 - annualreviews.org
Although microRNAs (miRNAs) are among the most intensively studied molecules of the past
20 years, determining what is and what is not a miRNA has not been straightforward. Here, …

[PDF][PDF] Vertebrate microRNA genes and CpG-islands

KL Ng, CH Huang, MC Tsai - WSEAS Transactions on Biology …, 2010 - researchgate.net
A portion of five vertebrate species microRNA (miRNA) genes are found to associate with
CpG-islands. It is calculated that 74 of 462 (16.0%), 37 of 373 (9.9%), 25 of 234 (10.7%), 25 of …

Computational prediction of amphioxus microRNA genes and their targets

Y Luo, S Zhang - Gene, 2009 - Elsevier
Using a homology search based on genomic survey sequence analysis and microRNA (miRNA)
secondary structure, a total of 51 miRNA genes encoding 30 amphioxus miRNAs were …

The evolution of animal microRNA function

R Niwa, FJ Slack - Current opinion in genetics & development, 2007 - Elsevier
MicroRNAs (miRNAs) are a large class of small RNAs that function as negative gene
regulators in eukaryotes. They regulate diverse biological processes, and bioinformatics data …

The expansion of the metazoan microRNA repertoire

J Hertel, M Lindemeyer, K Missal, C Fried, A Tanzer… - BMC genomics, 2006 - Springer
Background MicroRNAs have been identified as crucial regulators in both animals and
plants. Here we report on a comprehensive comparative study of all known miRNA families in …

Coding genes helped the origination and diversification of intragenic miRNAs

C Liu, X Zhang, J Yuan, J Xiang… - Molecular Biology and …, 2025 - academic.oup.com
Noncoding miRNAs tend to evolve within introns of coding genes who provide them with
transcriptional opportunity. As an outcome of natural selection, the intragenic position of …

Abundant and dynamically expressed miRNAs, piRNAs, and other small RNAs in the vertebrate Xenopus tropicalis

J Armisen, MJ Gilchrist, A Wilczynska… - Genome …, 2009 - genome.cshlp.org
Small regulatory RNAs have recently emerged as key regulators of eukaryotic gene expression.
Here we used high-throughput sequencing to determine small RNA populations in the …

Evolution of the miR199-214 cluster and vertebrate skeletal development

T Desvignes, A Contreras, JH Postlethwait - RNA biology, 2014 - Taylor & Francis
MicroRNA (miRs) are short non-coding RNAs that fine-tune the regulation of gene expression
to coordinate a wide range of biological processes. MicroRNAs are transcribed from miR …

Sex-biased microRNA expression in mammals and birds reveals underlying regulatory mechanisms and a role in dosage compensation

M Warnefors, K Mössinger, J Halbert, T Studer… - Genome …, 2017 - genome.cshlp.org
Sexual dimorphism depends on sex-biased gene expression, but the contributions of microRNAs
(miRNAs) have not been globally assessed. We therefore produced an extensive small …