Proteins of unknown function in the Protein Data Bank (PDB): an inventory of true uncharacterized proteins and computational tools for their analysis

N Nadzirin, M Firdaus-Raih - International journal of molecular sciences, 2012 - mdpi.com
… Using standard sequence and structure homology detection tools, we were able to provide
an accounting of the uncharacterized protein structures in the PDB that fit the two criteria …

Structure-based function prediction of uncharacterized protein using binding sites comparison

J Konc, M Hodošček, M Ogrizek… - PLoS computational …, 2013 - journals.plos.org
A challenge in structural genomics is prediction of the function of uncharacterized proteins.
When proteins cannot be related to other proteins of known activity, identification of function …

[HTML][HTML] From the uncharacterized protein family 0016 to the GDT1 family: molecular insights into a newly-characterized family of cation secondary transporters

L Thines, J Stribny, P Morsomme - Microbial Cell, 2020 - ncbi.nlm.nih.gov
The Uncharacterized Protein Family 0016 (UPF0016) gathers poorly studied membrane
proteins well conserved through evolution that possess one or two copies of the consensus …

[PDF][PDF] Computational structure analysis and function prediction of an uncharacterized protein (I6U7D0) of Pyrococcus furiosus Com1

AR Oany, SAI Ahmad, MAA Siddikey… - Austin J Comput Biol …, 2014 - researchgate.net
… function of an uncharacterized protein (I6U7D0) using various bioinformatic tools. … the
uncharacterized protein and the proteins that had structural similarity with uncharacterized protein

Structural and Functional Annotation of Uncharacterized Protein in Triticum aestivum

G Tandon, R Sharma, AK Mishra… - … of Bioinformatics and …, 2013 - indianjournals.com
… and possible functions for the uncharacterized protein (E2CZH4) of Triticum aestivum. With
the help of above findings we found that this uncharacterized protein has enzymatic activity, …

NovelFam3000–Uncharacterized human protein domains conserved across model organisms

D Kemmer, RM Podowski, D Arenillas, J Lim, E Hodges… - BMC genomics, 2006 - Springer
… From the Pfam domain database, we extracted uncharacterized protein domains represented
in proteins from humans, worms, and flies. A data centre was created to facilitate the …

In-silico prediction of an uncharacterized protein generated from heat responsive SSH library in wheat ('Triticum aestivum'L.)

JC Padaria, D Bhatt, K Biswas, G Singh… - Plant Omics, 2013 - search.informit.org
… For predicting function of this uncharacterized protein, in-… For finding signature sequence
that uncharacterized protein … confirmed that our uncharacterized protein under study belongs to …

PGRMC2, a yet uncharacterized protein with potential as tumor suppressor, migration inhibitor, and regulator of cytochrome P450 enzyme activity

A Wendler, M Wehling - Steroids, 2013 - Elsevier
PGRMC2 (progesterone receptor membrane component 2) is highly homologous if compared
with PGRMC1, a cytochrome-related protein, which is induced in several cancers and …

Bioinformatics Approaches for Structural and Functional Annotation of an Uncharacterized Protein of Helicobacter pylori

MM Alam, ASM Saikat, ME Uddin - Engineering Proceedings, 2023 - mdpi.com
… This uncharacterized protein could be helpful as a pharmacological target and marker if
annotated. According to the findings of various bioinformatic tools, software, and databases, the …

Structure based functional identification of an uncharacterized protein from Coxiella burnetii involved in adipogenesis

TI Mamun, M Bourhia, T Neoaj, S Akash, MAK Azad… - Scientific Reports, 2024 - nature.com
… Hypothetical proteins (HPs) are uncharacterized protein families or domains with unclear …
in-silico approach to characterize an uncharacterized protein from C. burnetii, hypothesized to …