Due to their architectural intricacy and biological significance, the synthesis of polycyclic
diterpenes and their biogenetically related alkaloids have been the subject of considerable …

… Moreover, the Mukaiyama aldol reaction using crotonaldehyde not only avoided the use
of acrolein but also paved the way for the enantioselective total synthesis of atropurpuran, of …

… Herein, we report a concise total synthesis of atropurpuran, a unique and synthetically
challenging pentacyclic diterpene that bears a tetracyclo[5.3.3.0 .0 4,12 ]-tridecane skeleton that is …

… the total synthesis of atropurpuran (5) and the arcutines (6). … that the first racemic total
synthesis of atropurpuran (1) was … Figure 4.7 Key steps in Qin's total synthesis of atropurpuran (…

… reported a convenient synthetic strategy for the total synthesis of atropurpuran (1) in 13 steps
… Once the core structure was built, the total synthesis of atropurpuran (1) was subsequently …

The first total synthesis of an arcutine-type C 20 -diterpenoid alkaloid arcutinine has been
achieved in both racemic and asymmetric forms. Construction of the C4 quaternary center and …

… In 2016, the Qin group reported their elegant first total synthesis of atropurpuran.[3] Three
years later, our research group also reported a total synthesis of atropurpuran.[4] Shortly after …

… While Kobayashi and coworkers did not ultimately complete a total synthesis of atropurpuran,
… a major advancement toward the total synthesis of atropurpuran, the completion of which …

Arcutinidine and other arcutinidine-type diterpenoid alkaloids feature an intricate polycyclic,
bridged framework with unusual connectivity. A chemical network analysis approach to the …

… By incorporating more densely functionalized building blocks early in the synthesis, they
were able to complete the second total synthesis of atropurpuran to date. Utilizing the same …