… In turn, somatostatin … somatostatin) are situated in intimate contact with the cells of origin of
insulin (B cell) and glucagon (A cell), has led most investigators to conclude that somatostatin …

… Nerve fibres that produce somatostatin have now been found in the genitourinary system, …
Actions of somatostatin As well as inhibiting the release of growth hormone somatostatin was …

… This chapter discusses the purification and characterization of somatostatin. Somatostatin
was … Synthetic somatostatin prepared by solid-phase methodology was found to be equipotent …

Somatostatin (SST), a regulatory peptide, is produced by neuroendocrine, inflammatory, and
immune cells in response to ions, nutrients, neuropeptides, neurotransmitters, thyroid and …

I. Introduction SOMATOSTATIN [somatotropin release-inhibiting factor (SRIF)] is a 14-amino
acid polypeptide that is widely distributed throughout the central nervous system and …

In 1972, Brazeau et al. isolated somatostatin (somatotropin release-inhibiting factor, SRIF),
a cyclic polypeptide with two biologically active isoforms (SRIF-14 and SRIF-28). This event …

This review summarizes the recent findings on the localization of somatostatin (SRIF)-related
peptides in local circuit interneurons and long projection neurons. These differential …

The diverse biological effects of somatostatin (SST) are mediated through a family of G protein
coupled receptors of which 5 members have been recently identified by molecular cloning…

… somatostatin receptors. A second native form of somatostatin was reported in 1980.2
Somatostatin 28 contains the amino acid sequence of somatostatin 14, extended by 14 residues at …

… The biological effects of somatostatin (SST) were first encountered unexpectedly in the late
… (b) Amino acid sequence of somatostatin isoforms depicting the cysteine bridge maintaining …