Effects of piperazine derivative on paclitaxel pharmacokinetics

J Lee, SW Chae, AR Oh, JH Yoo, HY Park Choo… - Pharmaceutics, 2019 - mdpi.com
… Therefore, P-gp inhibition by piperazine or its derivatives has not yet been elucidated. One
… However, although piperazine or its derivatives did not demonstrate a powerful effect on P-…

[HTML][HTML] The Impact of Incorporation Piperazine on Biological Activities of Benzazoles

T Al-Harthy, W Zoghaib, R Abdel-Jalil - 2024 - intechopen.com
… For this reason, some functional groups can be introduced to enhance the solubility eg,
piperazine or its derivatives. Based on their previous study, Xiang and his team are trying to …

Piperazine (and derivatives) Copper (II) compounds: 1, 4-dimethylpiperazin-1, 4-ium tetrachlorocuprate (II) and Cu N bond formation in trichloro (1-methylpiperazin-1 …

A Marzotto, DA Clemente, F Benetollo, G Valle - Polyhedron, 2001 - Elsevier
… The only paper reporting free piperazine or its derivatives chelated to Cu(II) is that of Kundu
et al. [13]. These authors, through Mössbauer, epr and magnetic spectra, stated that double …

Design, synthesis, molecular docking and biological activity of new piperidine and piperazine derivatives of dichloroacetate as potential anticancer agents

E Manouchehrizadeh, A Mostoufi… - Pharmaceutical …, 2020 - Springer
Dichloroacetate (DCA) is a small anticancer agent acting through inhibition of pyruvate
dehydrogenase kinases (PDKs) and preventing proliferation of tumor growth. In this study, a …

Piperazine reveals as a cell wall targeting antifungal agent against Candida albicans

A Jha, A Kumar - Gene Reports, 2024 - Elsevier
… Ultimately, our research indicates that piperazine or its derivatives may be a valuable
supplement to the antifungal arsenal, especially given the rise in multi-drug resistance in fungal …

Platinum (II) Complexes of Piperazine (and Derivatives): cis-Diiodo (N-methylpiperazine-N, N') platinum (II)

A Ciccarese, DA Clemente, FP Fanizzi… - … Section C: Crystal …, 1998 - journals.iucr.org
… The literature reports metal complexes in which piperazine or its derivatives act as
monodentate, bidentare or bidentate-chelate ligands. The chair conformation of the six-membered …

Reducing the reprocessing and healing temperature of polyurea with piperazine-based hindered urea bonds

FZ Wang, HQ Wang, WT Gao, CH Li - Materials Chemistry Frontiers, 2022 - pubs.rsc.org
… Four polymers containing different piperazinyl-urea units were synthesized through a one-step
polyaddition reaction of piperazine or its derivatives (Pz, MPz, trans-DMPz, and cis-DMPz…

Novel piperazine-containing oligomer as flame retardant and crystallization induction additive for thermoplastics polyurethane

H Chen, C Deng, ZY Zhao, L Wan, AH Yang… - Chemical Engineering …, 2020 - Elsevier
… in hard segments domain of TPU, and induce the occurrence of crystallization or greater
microphase separation in TPU, conclusively, TPU synthesized with piperazine or its derivatives

Pyridazinone: an important element of pharmacophore possessing broad spectrum of activity

S Dubey, PA Bhosle - Medicinal Chemistry Research, 2015 - Springer
… Compounds containing piperazine or its derivatives attached through nitrogen and bearing
phenyl ring substituted with CH 3 , C 2 H 5 , or OCH 3 were found to exhibit highly significant …

N, N′-diureylenepiperazine-bridged periodic mesoporous organosilica for controlled drug delivery

S Parambadath, VK Rana, D Zhao, CS Ha - Microporous and Mesoporous …, 2011 - Elsevier
… Giving emphasis to this point, the incorporation of piperazine or its derivatives into the
pore walls of the PMO would encourage future prospects in the pharmaceutical industry. The …