Perspectives for the Treatment of Infections withFlaviviridae
P Leyssen, E De Clercq, J Neyts - Clinical microbiology reviews, 2000 - Am Soc Microbiol
The family Flaviviridae contains three genera: Hepacivirus, Flavivirus, and Pestivirus. Worldwide,
more than 170 million people are chronically infected with Hepatitis C virus and are at …
more than 170 million people are chronically infected with Hepatitis C virus and are at …
Infections with flaviviridae.
J Neyts, P Leyssen, E De Clercq - … -Koninklijke Academie Voor …, 1999 - europepmc.org
The family of the Flaviviridae contains 3 genera:(i) the hepaciviruses, to which belongs
Hepatitis C virus (HCV),(ii) the flaviviruses and (iii) the pestiviruses. Over 140 million people, …
Hepatitis C virus (HCV),(ii) the flaviviruses and (iii) the pestiviruses. Over 140 million people, …
The epidemiology and disease burden of children hospitalized for viral infections within the family Flaviviridae in China: A national cross-sectional study
R Wang, X Wang, L Zhang, G Feng, M Liu… - PLoS Neglected …, 2022 - journals.plos.org
… The study described 490 children aged 0–15 years hospitalized for infections with Flaviviridae
viruses. Japanese encephalitis (JE) cases are the highest, accounting for 92.65% of the …
viruses. Japanese encephalitis (JE) cases are the highest, accounting for 92.65% of the …
An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological …
L Papageorgiou, S Loukatou, K Sofia… - Molecular …, 2016 - pubs.rsc.org
The rate of Flaviviridae family virus infections worldwide has increased dramatically in the last
few years. In addition, infections caused by arthropod vector viruses including Hepatitis C, …
few years. In addition, infections caused by arthropod vector viruses including Hepatitis C, …
Protein interactions during the flavivirus and hepacivirus life cycle
G Gerold, J Bruening, B Weigel… - Molecular & Cellular …, 2017 - ASBMB
Protein–protein interactions govern biological functions in cells, in the extracellular milieu,
and at the border between cells and extracellular space. Viruses are small intracellular …
and at the border between cells and extracellular space. Viruses are small intracellular …
Flaviviral infections and potential targets for antiviral therapy
A Baier - Flavivirus Encephalitis, 1st ed.; Ruzek, D., Ed.; InTech …, 2011 - books.google.com
… In humans infections with Flaviviridae may lead to fulminant, hemorrhagic diseaes [YFV,
DENV and omsk hemorrhagic fever virus (OHFV)], viral encephalitis [JEV, TBEV, WNV, St. Louis …
DENV and omsk hemorrhagic fever virus (OHFV)], viral encephalitis [JEV, TBEV, WNV, St. Louis …
Protein-driven membrane remodeling: Molecular perspectives from Flaviviridae infections
O Campbell, V Monje-Galvan - Biophysical Journal, 2023 - cell.com
The mammalian cell membrane consists of thousands of different lipid species, and this variety
is critical for biological function. Alterations to this balance can be dangerous as they can …
is critical for biological function. Alterations to this balance can be dangerous as they can …
A holistic evolutionary and structural study of flaviviridae provides insights into the function and inhibition of HCV helicase
Viral RNA helicases are involved in duplex unwinding during the RNA replication of the virus.
It is suggested that these helicases represent very promising antiviral targets. Viruses of …
It is suggested that these helicases represent very promising antiviral targets. Viruses of …
Characterization of targets for antiviral therapy of Flaviviridae infections
P Borowski - New Concepts of Antiviral Therapy, 2006 - Springer
The members of the Flaviviridae family are the cause of the explosively increasing number of
emerging infections of humans and economically important animals. Up to date there is no …
emerging infections of humans and economically important animals. Up to date there is no …
[HTML][HTML] Novel Pyrazino[1,2-a]indole-1,3(2H,4H)-dione Derivatives Targeting the Replication of Flaviviridae Viruses: Structural and Mechanistic Insights
E Giannakopoulou, I Akrani, G Mpekoulis, E Frakolaki… - Viruses, 2024 - mdpi.com
Infections with Flaviviridae viruses, such as hepatitis C (HCV), dengue (DENV), and yellow
fever (YFV) viruses, are major public health problems worldwide. In the case of HCV, …
fever (YFV) viruses, are major public health problems worldwide. In the case of HCV, …