Since the description of the first mouse knockout for an IgG Fc receptor seven years ago,
considerable progress has been made in defining the in vivo functions of these receptors in …

The complex family of human IgG Fc receptors show a wide cellular distribution and a strong
functional heterogeneity. To date, eight different genes that are transcribed into at least 12 …

… Besides phagocytes, such as granulocytes and monocytes, also lymphocytes and platelets
express members of the large family of IgG-Fc receptors or Fc gamma Rs. Three main …

Antibody-dependent enhancement (ADE) is a mechanism by which the pathogenesis of
certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non-…

… Human IgG Fc Receptors … This review addresses the molecular characteristics,
signaling pathways, and functions of IgG Fc receptors, focusing on the most recent findings. …

Immunoglobulins (Ig), a critical component of the adaptive immune system, are present in
all jawed vertebrates and through sophisticated diversification mechanisms are able to …

Considerable recent progress has been made in our understanding of how IgG immune
complexes interact with plasma membrane Fc receptors (FcR) to mediate a diversity of …

Human monocyte-derived DCs (moDCs) and circulating conventional DCs coexpress
activating (CD32a) and inhibitory (CD32b) isoforms of IgG Fcγ receptor (FcγR) II (CD32). The …

B lymphocytes and macrophages express closely related immunoglobulin G (IgG) Fc receptors
(FcγRII) that differ only in the structures of their cytoplasmic domains. Because of cell type…

Fc receptors for IgG (FcγRs) can trigger the inflammatory, cytotoxic and hypersensitivity
functions of immune effector cells. Activation or deactivation of effector cells via FcγRs can be …