Human stem cells for CNS repair

R Zietlow, EL Lane, SB Dunnett, AE Rosser - Cell and tissue research, 2008 - Springer
Although most peripheral tissues have at least a limited ability for self-repair, the central
nervous system (CNS) has long been known to be relatively resistant to regeneration. Small …

Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor β and Notch signaling

AP Robinson, JE Foraker, J Ylostalo… - Stem cells and …, 2011 - liebertpub.com
Multipotent stem/progenitor cells from bone marrow stroma (mesenchymal stromal cells or
MSCs) were previously shown to enhance proliferation and differentiation of neural stem cells …

Electrospun polyurethane scaffolds for proliferation and neuronal differentiation of human embryonic stem cells

B Carlberg, MZ Axell, U Nannmark, J Liu… - Biomedical …, 2009 - iopscience.iop.org
Adult central nervous system (CNS) tissue has a limited capacity to recover after trauma or
disease. Hence, tissue engineering scaffolds intended for CNS repair and rehabilitation have …

Progress and prospects: stem cells and neurological diseases

S Gögel, M Gubernator, SL Minger - Gene therapy, 2011 - nature.com
The central nervous system has limited capacity of regenerating lost tissue in slowly progressive,
degenerative neurological conditions such as Parkinson's disease (PD), Alzheimer's …

Stem cells for the treatment of neurodegenerative diseases

YP Wu, WS Chen, C Teng, N Zhang - Molecules, 2010 - mdpi.com
Neurodegenerative diseases are characterized by neurodegenerative changes or apoptosis
of neurons involved in networks, leading to permanent paralysis and loss of sensation …

Stem cells: established facts, open issues, and future directions

G Kuhn, O Brüstle, U Martens, A Wobus… - Cell and Tissue …, 2008 - Springer
… Zietlow and associates (2007) review the potential of human stem cells for CNS repair in
general, whereas Morizane et al. (2007) focus on the potential of neural, embryonic, and other …

[PDF][PDF] Potential roles of the neural stem cell in the restoration of the injured spinal cord: review of the literature

S Kabatas - Turkish Neurosurgery, 2010 - turkishneurosurgery.org.tr
The use of stem cells in the treatment of traumatic spinal cord injury (SCI) in recent years
has provided promising results. Different sources of cells for transplantation have been used, …

Stem cell-based therapies for spinal cord injury

RS Nandoe Tewarie, A Hurtado… - The journal of spinal …, 2009 - Taylor & Francis
Spinal cord injury (SCI) results in loss of nervous tissue and consequently loss of motor and
sensory function. There is no treatment available that restores the injury-induced loss of …

Stem cells in the treatment of chronic spinal cord injury: evaluation of somatosensitive evoked potentials in 39 patients

AF Cristante, TEP Barros-Filho, N Tatsui, A Mendrone… - Spinal cord, 2009 - nature.com
Study design: A prospective, non-randomized clinical series trial. Objective: To evaluate the
effect of autogenous undifferentiated stem cell infusion for the treatment of patients with …

Regeneration of completely transected spinal cord using scaffold of poly (D, L-lactide-co-glycolide)/small intestinal submucosa seeded with rat bone marrow stem …

KN Kang, JY Lee, DY Kim, BN Lee, HH Ahn… - … Engineering Part A, 2011 - liebertpub.com
Using a complete spinal cord transection model, the present study employed a combinatorial
strategy comprising rat bone marrow stem cells (rBMSCs) and polymer scaffolds to …