OBJECTIVE: Advances in image-guided stereotactic surgery, microelectrode recording
techniques, and stimulation technology have been the driving forces behind a resurgence in
the use of functional neurosurgery for the treatment of movement disorders. Despite the
dramatic effects of deep brain stimulation (DBS) techniques in ameliorating the symptoms of
Parkinson's disease, many critical questions related to the targeting, effects, and
mechanisms of action of DBS remain unanswered. In this report, we describe the methods …