… for vaccines for chronic infections and for cancer therapy, these discoveries in immunology
come at an opportune time to be exploited in the development of new generation vaccines. …

The history of immunization, from the earliest attempts to modern, genetically engineered
vaccine candidates, represents a long road marked with many milestones. Extensive historical …

… In this paper we will discuss general immunological requirements for the induction of effective
and durable immunity with the new generation vaccines, based on principles which began …

Cholera is a major global health problem, causing approximately 100,000 deaths annually,
about half of which occur in sub-Saharan Africa. Although early-generation parenteral …

… For the new generation vaccines, it is an important, but incomplete, step. We now know
that antigens induce a protective immune response only if they are introduced to the immune …

… Especially in underdeveloped countries, affordability of new generation vaccines will be
critically important for reducing disease transmission in both human and livestock species. As a …

Initial vaccine attempts to prevent infectious diseases were in 1000 AD in China, whereby
the contents of smallpox vesicles were used to inject healthy individuals who were …

Vaccinology continues, impressively, to advance and mature both in the development of
new and improved vaccines and in the implementation of vaccines to prevent disease, thus …

Despite the existence of a highly efficient yellow fever vaccine, yellow fever reemergence
throughout Africa and the Americas has put 900 million people in 47 countries at risk of …

… some recent approaches in the development of new-generation vaccines with special … few
decades and keep evolving to create new-generation vaccines. Source: Based on a modified …