Nucleic acid vaccines

FR Vogel, N Sarver - Clinical microbiology reviews, 1995 - Am Soc Microbiol
The use of nucleic acid-based vaccines is a novel approach to immunization that elicits
immune responses similar to those induced by live, attenuated vaccines. Administration of …

The promise of nucleic acid vaccines

NP Restifo, H Ying, L Hwang, WW Leitner - Gene therapy, 2000 - nature.com
… trials is scant: nucleic acid vaccines have not been clearly … to the real success of nucleic
acid vaccines in the prevention … therefore refer to them collectively as nucleic acid vaccines. …

RNA: the new revolution in nucleic acid vaccines

AJ Geall, CW Mandl, JB Ulmer - Seminars in immunology, 2013 - Elsevier
Nucleic acid vaccines have the potential to address issues of safety and effectiveness … In
addition, methods to manufacture nucleic acid vaccines are suitable as generic platforms and …

The application of nucleic acid vaccines in veterinary medicine

SP Dunham - Research in veterinary science, 2002 - Elsevier
Nucleic acid vaccines offer the potential for further advancements in the production of safe
and effective vaccines. The principle for such vaccines is elegantly simple. DNA (or more …

Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines

RP Deering, S Kommareddy, JB Ulmer… - Expert opinion on …, 2014 - Taylor & Francis
… Like other types of nucleic acid vaccines, mRNA vaccines have the potential to combine the
positive attributes of live attenuated vaccines while obviating many potential safety limitations…

[HTML][HTML] Advances in the polymeric delivery of nucleic acid vaccines

G Chen, B Zhao, EF Ruiz, F Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
… relevant to nucleic acid vaccines and their delivery using polymer-based systems. Finally,
we summarize the strategies for enhancing the efficacy of nucleic acid vaccines in the …

A guide to nucleic acid vaccines in the prevention and treatment of infectious diseases and cancers: from basic principles to current applications

F Qin, F Xia, H Chen, B Cui, Y Feng, P Zhang… - Frontiers in cell and …, 2021 - frontiersin.org
… of the nucleic acid vaccines. We next focused on the delivery of nucleic acid vaccines, with
an … Finally, we turned our attention to the clinical applications of nucleic acid vaccines by …

Third-generation vaccines: features of nucleic acid vaccines and strategies to improve their efficiency

ARS Melo, LS de Macêdo, MCV Invenção, IA de Moura… - Genes, 2022 - mdpi.com
… new models and approaches for designing nucleic acid vaccines. Particularly with viral
infections, … of nucleic acid vaccines, emphasizing the design of synthetic multi-epitope antigens. …

Nucleic acid vaccines for COVID-19: a paradigm shift in the vaccine development arena

VP Chavda, MK Hossain, J Beladiya, V Apostolopoulos - Biologics, 2021 - mdpi.com
Nucleic acid vaccines employ genetic material from a pathogen… Nucleic acid vaccines for
multiple antigens might be made in … and advances in nucleic acid vaccines (DNA and mRNA …

Nucleic acid vaccines against SARS-CoV-2

Y Liu, Q Ye - Vaccines, 2022 - mdpi.com
Nucleic acid vaccines are viral genetic sequence-based vaccines and third-generation …
research and development processes of nucleic acid vaccines, summarize the advantages and …