Function and Biology Details
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
TAR DNA-binding protein 43 and RNA (preferred)
PDBe Complex ID:
PDB-CPX-171559 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
TAR DNA-binding protein 43
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 20 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
Length: 174 amino acids
Theoretical weight: 20 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q13148 (Residues: 102-269; Coverage: 41%)
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
92%
Refinement method:
SIMULATED ANNEALING COMBINED WITH MOLECULAR DYNAMICS IN TORSION ANGLE SPACE
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided