Abstract
Background
The introduction of non-invasive prenatal testing (NIPT) for Down's syndrome into routine state-funded antenatal care in the UK is approaching.Methods
We conducted qualitative one-to-one interviews with 40 pregnant women to ascertain their views on using NIPT for Down's syndrome.Results
The overwhelming majority of women viewed NIPT as a positive advancement in prenatal care, highlighting numerous practical and psychological advantages of a safe test that was highly accurate and could be conducted early in pregnancy. Concerns raised were that testing could become routinised, and that pressure to test might occur with women feeling less justified in declining a blood test that is available and offered by trusted health professionals; the impact on the disabled community and stigma for women who decline testing was also noted. Nevertheless, the vast majority of women said they would be likely to use NIPT, including half of the women who currently decline screening. Women's preference was for pre- and post-test counselling to be delivered by a midwife.Conclusion
The successful introduction of NIPT into routine prenatal care will require guidelines and counselling strategies which ensure women are offered this test in a way which safeguards informed consent.Citations & impact
Impact metrics
Article citations
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Review
Funding
Funders who supported this work.
Great Ormond Street Hospital Childrens Charity (1)
Grant ID: V1253
National Institute for Health Research (NIHR) (1)
Reliable Accurate Prenatal non-Invasive Diagnosis (RAPID) - an integrated project to refine and implement safer antenatal testing.
Professor Lyn Chitty, Great Ormond Street Hospital for Children NHS Foundation Trust
Grant ID: RP-PG-0707-10107