Concomitant germ-line RUNX1 and acquired ASXL1 mutations in a T-cell acute lymphoblastic leukemia.

Prebet T ^{1,

4},

Carbuccia N ²,

Raslova H ³,

Favier R ³,

Mozziconacci MJ ^{2,

5}

Affiliations

1. Faculté de Médecine, Aix-Marseille Université, Marseille, France.
Authors
Prebet T^{1,

4}
Vey N^{1,

4}
(2 authors)
2. Centre de Recherche en Cancérologie de Marseille, Laboratoire d'Oncologie Moléculaire, UMR1068 Inserm, Institut Paoli-Calmettes, Marseille, France.
Authors
Carbuccia N²
Birnbaum D²
Mozziconacci MJ^{2,

5}
(3 authors)
3. INSERM U1009, Institut Gustave Roussy, Villejuif, France.
Authors
Raslova H³
Favier R³
Vainchenker W³
(3 authors)
4. Département d'Hématologie, Institut Paoli-Calmettes, Marseille, France.
Authors
Prebet T^{1,

4}
Rey J⁴
Vey N^{1,

4}
(3 authors)
5. Département de BioPathologie, Institut Paoli-Calmettes, Marseille, France.
Authors
Arnoulet C⁵
Mozziconacci MJ^{2,

5}
(2 authors)

ORCIDs linked to this article

European Journal of Haematology, 28 Jun 2013, 91(3):277-279
https://doi.org/10.1111/ejh.12147 PMID: 23692290

Abstract

No abstract provided.

Full text links

Read article at publisher's site: https://doi.org/10.1111/ejh.12147

References

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.
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Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias.
Rocquain J, Carbuccia N, Trouplin V, Raynaud S, Murati A, Nezri M, Tadrist Z, Olschwang S, Vey N, Birnbaum D, Gelsi-Boyer V, Mozziconacci MJ
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Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.
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J Hematol Oncol, 12 2012
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Mutations and deletions of the SUZ12 polycomb gene in myeloproliferative neoplasms.
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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Search life-sciences literature (45,100,050 articles, preprints and more)

Concomitant germ-line RUNX1 and acquired ASXL1 mutations in a T-cell acute lymphoblastic leukemia.

Affiliations

ORCIDs linked to this article

Abstract

Full text links

References

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.

The origin and evolution of mutations in acute myeloid leukemia.

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Myeloid malignancies: mutations, models and management.

Familial myelodysplasia and acute myeloid leukaemia--a review.

Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia.

Integrated profiling of basal and luminal breast cancers.

Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias.

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.

Mutations and deletions of the SUZ12 polycomb gene in myeloproliferative neoplasms.

Citations & impact

Impact metrics

Citations of article over time

Article citations

Epigenetic regulation by ASXL1 in myeloid malignancies.

Novel Germline RUNX1 Mutation Associated with Familial Thrombocytopenia as well as B-Acute Lymphoblastic Leukemia: A Case Report and Review of the Literature.

Secondary leukemia in patients with germline transcription factor mutations (RUNX1, GATA2, CEBPA).

The development of T-cell malignancies in patients with pre-existing myeloproliferative neoplasms: a report of three cases.

Recent advances in genetic predisposition to pediatric acute lymphoblastic leukemia.

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Concomitant germ-line RUNX1 and acquired ASXL1 mutations in a T-cell acute lymphoblastic leukemia.

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