Europe PMC
Nothing Special   »   [go: up one dir, main page]

Europe PMC requires Javascript to function effectively.

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page.

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Nesfatin-1 stimulates renal sympathetic nerve activity in rats.

Author information

Affiliations

  • 1. Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan.
      Authors
    • Tanida M 1
    (1 author)

Neuroreport, 01 Apr 2011, 22(6):309-312
https://doi.org/10.1097/wnr.0b013e328346107f PMID: 21451359 

Abstract 

Earlier examination reported that central injection of nesfatin-1 elevated blood pressure and suppressed food intake in conscious rats. In this study, we analyzed the effects of the intracerebroventricular injection of nesfatin-1 on the sympathetic nerve outflow to the kidney in urethane-anesthetized rats. An intracerebroventricular injection of nesfatin-1 significantly stimulated renal sympathetic nerve activity and blood pressure in a dose-dependent manner. Moreover, we examined the role of the melanocortin system on the sympathoexcitation caused by the nesfatin-1 injection. Pretreatment with the melanocortin-3/4 receptor antagonist, SHU9119, abolished the increase in nerve activity and blood pressure induced by nesfatin-1. Thus, the stimulating effects of nesfatin-1 administration on the sympathetic nerve activity of the kidney may depend on the central melanocortin system.

Full text links 

Read article at publisher's site: https://doi.org/10.1097/wnr.0b013e328346107f

Subscription required at www.neuroreport.com
http://content.wkhealth.com/linkback/openurl?issn=0959-4965&volume=22&issue=6&spage=309

Citations & impact 

Impact metrics

33
Citations
Jump to Citations

Citations of article over time

Alternative metrics

Altmetric item for https://www.altmetric.com/details/703155
Altmetric
Discover the attention surrounding your research
https://www.altmetric.com/details/703155

Smart citations by scite.ai
Smart citations by scite.ai include citation statements extracted from the full text of the citing article. The number of the statements may be higher than the number of citations provided by EuropePMC if one paper cites another multiple times or lower if scite has not yet processed some of the citing articles.
Explore citation contexts and check if this article has been supported or disputed.
https://scite.ai/reports/10.1097/wnr.0b013e328346107f

Supporting
Mentioning
Contrasting
2
39
1

Article citations

Go to all (33) article citations

Similar Articles 

To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.