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The genome of the model beetle and pest Tribolium castaneum.

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Affiliations

  • 1. Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.
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Nature, 23 Mar 2008, 452(7190):949-955
https://doi.org/10.1038/nature06784 PMID: 18362917 

Abstract 

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell-cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.

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Read article at publisher's site: https://doi.org/10.1038/nature06784

Read article for free, from open access legal sources, via Unpaywall: https://www.nature.com/articles/nature06784.pdfUnpaywall

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Funding 

Funders who supported this work.

Biotechnology and Biological Sciences Research Council (2)

Intramural NIH HHS

    NICHD NIH HHS (2)

    Telethon (1)