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The mathematical theory of single outbreak epidemic models really
began with the work of Kermack and Mackendrick about $8$ decades
ago. This gave a simple answer to the long-standing question of why
epidemics woould appear suddenly and then disappear just as suddenly
without having infected an entire population. Therefore it seemed
natural to expect that theoreticians would immediately proceed to
expand this mathematical framework both because the need to handle
recurrent single infectious disease outbreaks has always been a
priority for public health officials and because theoreticians often
try to push the limits of exiting theories. However, the expansion
of the theory via the inclusion of refined epidemiological
classifications or through the incorporation of categories that are
essential for the evaluation of intervention strategies, in the
context of ongoing epidemic outbreaks, did not materialize. It was
the global threat posed by SARS in $2003$ that caused theoreticians
to expand the Kermack-McKendrick single-outbreak framework. Most
recently, efforts to connect theoretical work to data have exploded
as attempts to deal with the threat of emergent and re-emergent
diseases including the most recent H1N1 influenza pandemic, have
marched to the forefront of our global priorities. Since data are
collected and/or reported over discrete units of time, developing
single outbreak models that fit collected data naturally is
relevant. In this note, we introduce a discrete-epidemic framework
and highlight, through our analyses, the similarities between
single-outbreak comparable classical continuous-time epidemic models
and the discrete-time models introduced in this note. The emphasis
is on comparisons driven by expressions for the final epidemic size.
Citation: Fred Brauer, Zhilan Feng, Carlos Castillo-Chávez. Discrete epidemic models[J]. Mathematical Biosciences and Engineering, 2010, 7(1): 1-15. doi: 10.3934/mbe.2010.7.1
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Abstract
The mathematical theory of single outbreak epidemic models really
began with the work of Kermack and Mackendrick about $8$ decades
ago. This gave a simple answer to the long-standing question of why
epidemics woould appear suddenly and then disappear just as suddenly
without having infected an entire population. Therefore it seemed
natural to expect that theoreticians would immediately proceed to
expand this mathematical framework both because the need to handle
recurrent single infectious disease outbreaks has always been a
priority for public health officials and because theoreticians often
try to push the limits of exiting theories. However, the expansion
of the theory via the inclusion of refined epidemiological
classifications or through the incorporation of categories that are
essential for the evaluation of intervention strategies, in the
context of ongoing epidemic outbreaks, did not materialize. It was
the global threat posed by SARS in $2003$ that caused theoreticians
to expand the Kermack-McKendrick single-outbreak framework. Most
recently, efforts to connect theoretical work to data have exploded
as attempts to deal with the threat of emergent and re-emergent
diseases including the most recent H1N1 influenza pandemic, have
marched to the forefront of our global priorities. Since data are
collected and/or reported over discrete units of time, developing
single outbreak models that fit collected data naturally is
relevant. In this note, we introduce a discrete-epidemic framework
and highlight, through our analyses, the similarities between
single-outbreak comparable classical continuous-time epidemic models
and the discrete-time models introduced in this note. The emphasis
is on comparisons driven by expressions for the final epidemic size.
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