The Neuron Registry Curator Interface: an Infrastructure for the Collaborative Definition of Neuronal Properties
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1
George Mason University, Center for Neural Informatics, Structure, and Plas, United States
Classifying neurons based on their properties is a fundamental goal in neuroscience (Petilla Interneuron Nomenclature Group: Ascoli et al., Nature Rev Neurosci, 2008). To catalyze progress, the International Neuroinformatics Coordination Facility (INCF) recently organized a Task Force for the creation of a Neuron Registry under the Program on Ontologies of Neural Structures (www.incf.org/core/programs/pons). Our research aims at developing an infrastructure to facilitate the necessary collaboration among the Task Force domain experts. In particular, we describe the implementation of a Neuron Registry Curator Interface (incfnrci.appspot.com) for identifying the necessary and sufficient properties to define neuron types. This web-based database front-end is synchronized with the Neuroscience Information Framework (NIF) vocabularies contained in NeuroLex.Org. The easily learned, broadly accessible, and usage-friendly entry-form with pre-populated vocabularies registered with a robust repository, is meant to funnel the world's forefront expertise on neuronal properties and types to form a consensus on neuron classification.
Supported by NINDS R01 NS39600, by NIDA under the NIH Blueprint for Neuroscience via a NIF sub-contract, and by INCF.
Conference:
Neuroinformatics 2010 , Kobe, Japan, 30 Aug - 1 Sep, 2010.
Presentation Type:
Oral Presentation
Topic:
General neuroinformatics
Citation:
Hamilton
DJ and
Ascoli
GA
(2010). The Neuron Registry Curator Interface: an Infrastructure for the Collaborative Definition of Neuronal Properties.
Front. Neurosci.
Conference Abstract:
Neuroinformatics 2010 .
doi: 10.3389/conf.fnins.2010.13.00075
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Received:
14 Jun 2010;
Published Online:
14 Jun 2010.
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Correspondence:
David J Hamilton, George Mason University, Center for Neural Informatics, Structure, and Plas, Fairfax, United States, dhamilt5@gmu.edu