Nothing Special   »   [go: up one dir, main page]
Skip to main content
Springer Nature Link
Log in

MYB transcription factor genes as regulators for plant responses: an overview

  • Review Article
  • Published:
Physiology and Molecular Biology of Plants Aims and scope Submit manuscript

Abstract

Regulation of gene expression at the level of transcription controls many crucial biological processes. Transcription factors (TFs) play a great role in controlling cellular processes and MYB TF family is large and involved in controlling various processes like responses to biotic and abiotic stresses, development, differentiation, metabolism, defense etc. Here, we review MYB TFs with particular emphasis on their role in controlling different biological processes. This will provide valuable insights in understanding regulatory networks and associated functions to develop strategies for crop improvement.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  • Abe H, Urao T, Ito T, Seki M, Shinozaki K, Yamaguchi-Shinozaki K (2003) Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) function as transcriptional activators in abscisic acid signaling. Plant Cell 15:63–78

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Agarwal M et al (2006) A R2R3 type MYB transcription factor is involved in the cold regulation of CBF genes and in acquired freezing tolerance. J Biol Chem 281:37636–37645

    Article  CAS  PubMed  Google Scholar 

  • Akagi T, Ikegami A, Yonemori K (2010) DkMyb2 wound-induced transcription factor of persimmon (Diospyros kaki Thunb.), contributes to proanthocyanidin regulation. Planta 232:1045–1059

    Google Scholar 

  • Baumann K, Rodriguez MP, Bradley D, Venail J, Bailey P, Jin H, Koes R, Roberts K, Martin C (2007) Control of cell and petal morphogenesis by R2R3 MYB transcription factors. Development 134:1691–1701

    Article  CAS  PubMed  Google Scholar 

  • Borg M, Brownfield L, Khatab H, Sidorova, Lingaya M, Twell D (2011) The R2R3 MYB transcription factor DUO1 activates a male germline-specific regulon essential for sperm cell differentiation in Arabidopsis. Plant Cell 23:2534–2549. doi:10.1105/tpc.110.081059

    Article  CAS  Google Scholar 

  • Bray EA (1997) Plant responses to water deficit. Trends Plant Sci 2:48–54

    Article  Google Scholar 

  • Brownfield L et al (2009) A plant germline-specific integrator of sperm specification and cell cycle progression. PLoS Genet 5:e1000430

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Century K, Reuber TL, Ratcliffe OJ (2008) Regulating the regulators: the future prospects for transcription-factor based agricultural biotechnology products. Plant Physiol 147:20–29

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chen S, Peng S, Huang G, Wu K, Fu X, Chen Z (2003) Association of decreased expression of a Myb transcription factor with the TPD (tapping panel dryness) syndrome in Hevea brasiliensis. Plant Mol Biol 51:51–58

    Article  CAS  PubMed  Google Scholar 

  • Chen B-J, Wang Y, Hu YL, Wu Q, Lin ZP (2005a) Cloning and characterization of a drought inducible MYB gene from Boea crassifolia. Plant Sci 168:493–500

    Article  CAS  Google Scholar 

  • Chen R, Ni Z, Nie X, Qin Y, Dong G, Sun Q (2005b) Isolation and characterization of genes encoding Myb transcription factor in wheat (Triticum aestivum L.). Plant Sci 169:1146–1154

    Article  CAS  Google Scholar 

  • Cheng H et al (2009) Gibberellin acts through jasmonate to control the expression of MYB21, MYB24, and MYB57 to promote stamen filament growth in Arabidopsis. PLoS Genet 5:e1000440

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Cheong YH, Chang HS, Gupta R, Wang X, Zhu T, Luan S (2002) Transcriptional profiling reveals novel interactions between wounding, pathogen, abiotic stress, and hormonal responses in Arabidopsis. Plant Physiol 129:661–677

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chuan YH, Johnie N, Jenkins A, Sukumar SH, Din PM (2005) Transcriptional regulation of the lipid transfer protein gene LTP3 in cotton fibers by a novel MYB protein. Plant Sci 168:167–181

    Article  CAS  Google Scholar 

  • Cominelli E et al (2005) A guard-cell-specific MYB transcription factor regulates stomatal movements and plant drought tolerance. Curr Biol 15:1196–1200

    Article  CAS  PubMed  Google Scholar 

  • Cone KC, Burr FA, Burr B (1986) Molecular analysis of the maize anthocyanin regulatory locus C1. Proc Natl Acad Sci U S A 83:9631–9635

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cone KC, Cocciolone SM, Burr FA, Burr B (1993) Maize anthocyanin regulatory gene pl is a duplicate c1 that functions in the plant. Plant Cell 5:1795–1805

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dai X, Xu Y, Ma Q, Xu W, Wang T, Xue Y, Chong K (2007) Overexpression of an R1R2R3 MYB gene OsMYB3R-2, increases tolerance to freezing, drought, salt stress in transgenic Arabidopsis. Plant Physiol 143:739–1751

    Google Scholar 

  • Dai X, Wang Y, Yang A, Zhang WH (2012) OsMYB2P-1, an R2R3 MYB transcription factor, is involved in the regulation of phosphate-starvation responses and root architecture in rice. Plant Physiol 159:169–183

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • De Vos M et al (2006) The Arabidopsis thaliana transcription factor AtMYB102 functions in defense against the insect herbivore Pieris rapae. Plant Signal Behav 1:305–311

    Google Scholar 

  • Denekamp M, Smeekens SC (2003) Integration of wounding and osmotic stress signals determines the expression of the AtMYB102 transcription factor gene. Plant Physiol 132:1415–1423

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Devaiah BN, Madhuvanthi R, Athikkattuvalasu R, Karthikeyan S, Raghothama KG (2009) Phosphate starvation responses and gibberellic acid biosynthesis are regulated by the MYB62 transcription factor in Arabidopsis. Mol Plant 2:43–58

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Du H, Zhang L, Liu L, Tang XF, Yang WJ, Wu YM, Huang YB, Tang YX (2009) Biochemical and molecular characterization of plant MYB transcription factor family. Biochemistry 74:1–11

    CAS  PubMed  Google Scholar 

  • Du H, Feng BR, Yang SS, Huang YB, Tang YX (2012a) The R2R3-MYB transcription factor gene family in maize. PLoS One 7(6):e37463. doi:10.1371/journal.pone.0037463

    Article  PubMed  PubMed Central  Google Scholar 

  • Du H, Yang SS, Liang Z, Feng BR, Liu L, Huang YB, Tang YX (2012b) Genome-wide analysis of the MYB transcription factor superfamily in soybean. BMC Plant Biol 12:106

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dubos C, Gourrierec JL, Baudry A, Huep G, Lanet E, Debeaujon I, Routaboul JM, Alboresi A, Weisshaar B, Lepiniec L (2008) MYBL2 is a new regulator of flavonoid biosynthesis in Arabidopsis thaliana. Plant J 55:940–953

    Article  CAS  PubMed  Google Scholar 

  • Dubos C, Stracke R, Grotewold E, Weisshaar B, Martin C, Lepiniec L (2010) MYB transcription factors in Arabidopsis. Trends Plant Sci 15:573–581

    Article  CAS  PubMed  Google Scholar 

  • El-kereamy A, Bi Y-M, Ranathunge K, Beatty PH, Good AG et al (2012) The rice R2R3-MYB transcription factor OsMYB55 is involved in the tolerance to high temperature and modulates amino acid metabolism. PLoS One 7(12):e52030. doi:10.1371/journal.pone.0052030

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Feldbrugge M, Sprenger M, Hahlbrock K, Weisshaar B (1997) PcMYB1 novel plant protein containing a DNA-binding domain with one Myb repeat, interacts in vivo with a light-regulatory promoter unit. Plant J 11:1079–1093

    Article  CAS  PubMed  Google Scholar 

  • Feng C, Andressson E, Maslak A, Mock HP, Mattsson O, Mundy L (2004) Arabidopsis MYB68 in development and responses to environmental cues. Plant Sci 167:1099–1107

    Article  CAS  Google Scholar 

  • Fornale S et al (2010) ZmMYB31 directly represses maize lignin genes and redirects the phenylpropanoid metabolic flux. Plant J 64(4):633–644

    Google Scholar 

  • Gigolashvili T et al (2007) The transcription factor HIG1/MYB51 regulates indolic glucosinolate biosynthesis in Arabidopsis thaliana. Plant J 50:886–901

    Article  CAS  PubMed  Google Scholar 

  • Gigolashvili T et al (2008) HAG2/MYB76 and HAG3/MYB29 exert a specific and coordinated control on the regulation of aliphatic glucosinolate biosynthesis in Arabidopsis thaliana. New Phytol 177:627–642

    Article  CAS  PubMed  Google Scholar 

  • Gocal GFW, Sheldon CC, Gubler F (2001) GAMyb-like gene, flowering and gibberellins signaling in Arabidopsis. Plant Physiol 127:682–1691

    Article  CAS  Google Scholar 

  • Gonzalez A, Zhao M, Leavitt JM, Lloyd AM (2008) Regulation of the anthocyanin biosynthetic pathway by the TTG1/bHLH/Myb transcriptional complex in Arabidopsis seedlings. Plant J 53:814–827

    Article  CAS  PubMed  Google Scholar 

  • Gonzalez A et al (2009) TTG1 complex MYBs, MYB5 and TT2, control outer seed coat differentiation. Dev Biol 325:412–421

    Article  CAS  PubMed  Google Scholar 

  • Grotewold E, Drummond BJ, Bowen B, Peterson T (1994) The myb-homologous P gene controls phlobaphene pigmentation in maize floral organs by directly activating a flavonoid biosynthetic gene subset. Cell 76:543–553

    Article  CAS  PubMed  Google Scholar 

  • Gubler F, Kalla R, Roberts JK, Jacobsen JV (1995) Gibberellin regulated expression of a myb gene in barley aleurone cells: evidence for Myb transactivation of a high-pl α amylase gene promoter. Plant Cell 7:1879–1891

    CAS  PubMed  PubMed Central  Google Scholar 

  • Gubler F, Watts RJ, Kalla R, Matthews P, Keys M, Jacobsen JV (1997) Cloning of rice cDNA encoding a transcription factor homologous to barley GAMyb. Plant Cell Physiol 38:362–365

    Article  CAS  PubMed  Google Scholar 

  • Hichri I, Barrieu F, Bogs J, Kappel C, Delrot S, Lauvergeat V (2011) Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway. J Exp Bot 62(8):2465–2483

    Google Scholar 

  • Higginson T, Li SF, Parish RW (2003) AtMYB103 regulates tapetum and trichome development in Arabidopsis thaliana. Plant J 35:177–192

    Article  CAS  PubMed  Google Scholar 

  • Hirai MY, Sugiyama K, Sawada Y et al (2007) Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis. Proc Natl Acad Sci U S A 104:6478–6483

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hoeren FU, Dolferus R, Wu Y, Peacock WJ, Dennis ES (1998) Evidence for a role for AtMYB2 in the induction of the Arabidopsis alcohol dehydrogenase gene (ADH1) by low oxygen. Genetics 149:479–490

    CAS  PubMed  PubMed Central  Google Scholar 

  • Huang W, Sun W, Lv H, Xiao G, Zeng S, Wang Y (2013) Isolation and molecular characterization of thirteen R2R3-MYB transcription factors from Epimedium sagittatum. Int J Mol Sci 14:594–610. doi:10.3390/ijms14010594

    Article  CAS  PubMed Central  Google Scholar 

  • Ishida T, Hattori S, Sano R, Inoue K, Shirano Y, Hayashi H, Shibata D, Sato S, Kato T, Tabata S, Okada K, Wada T (2007) Arabidopsis TRANSPARENT TESTA GLABRA2 is directly regulated by R2R3 MYB transcription factors and is involved in regulation of GLABRA2 transcription in epidermal differentiation. Plant Cell 19:2531–2543

    Google Scholar 

  • Ito M, Araki S, Matsunaga S, Itoh T, Nishihama R, Machida Y, Doonan JH, Watanabe A (2001) G2/M-phase-specific transcription during the plant cell cycle is mediated by c-Myb-like transcription factors. Plant Cell 13:1891–1906

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Iturriaga G, Leyns L, Villeges A, Gharaibeh R, Salamini F, Bartels D (1996) A family of novel myb-related genes from the resurrection plant Craterostigma plantagineum are specifically expressed in callus and roots in response to ABA or dessication. Plant Mol Biol 32:707–716

    Google Scholar 

  • Jackson D, Culianez-Macia F, Prescott AG, Roberts K, Martin C (1991) Expression patterns of myb genes from Antirrhinum flowers. Plant Cell 3:115–125

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jiang C et al (2004a) Ordered origin of the typical two- and three-repeat Myb genes. Gene 326:13–22

    Google Scholar 

  • Jiang C, Gu X, Peterson T (2004b) Identification of conserved gene structures and carboxy-terminal motifs in the Myb gene family of Arabidopsis and Oryza sativa L. ssp. indica. Genome Biol 5:R46

    Article  PubMed  PubMed Central  Google Scholar 

  • Jin H, Martin C (1999) Multifunctionality and diversity within the plant MYB-gene family. Plant Mol Biol 41(5):577–585

    Article  CAS  PubMed  Google Scholar 

  • Jin H, Cominelli E, Bailey P, Parr A, Mehrtens F, Jones J, Tonelli C, Weisshaar B, Martin C (2000) Transcriptional repression by AtMYB4 controls production of UV- protecting sunscreens in Arabidopsis. EMBO J 19:6150–6161

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Johnson ET, Dowd PF (2004) Differentially enhanced insect resistance, at a cost, in Arabidopsis thaliana constitutively expressing a transcription factor of defensive metabolites. J Agric Food Chem 52:5135–5138

    Article  CAS  PubMed  Google Scholar 

  • Jung C et al (2008) Overexpression of AtMYB44 enhances stomatal closure to confer abiotic stress tolerance in transgenic Arabidopsis. Plant Physiol 146:623–635

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kang YH, Kirik V, Hulskamp M, Nam KH, Hagely K, Lee MM, Schiefelbein J (2009) The MYB23 gene provides a positive feedback loop for cell fate specification in the Arabidopsis root epidermis. Plant Cell 21:1080–1094

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kazan K (2006) Negative regulation of defense and stress genes by EAR-motif-containing repressors. Trends Plant Sci 11:109–112

    Article  CAS  PubMed  Google Scholar 

  • Kizis D, Lumbreras V, Pages M (2001) Role of AP2/EREBP transcription factors in gene regulation during abiotic stress. FEBS Lett 498:187–189

    Article  CAS  PubMed  Google Scholar 

  • Kranz HD, Denekamp M, Greco R, Jin HL, Leyva A, Meissner R, Petroni K, Urzainqui A, Bevan M, Martin C, Smeekens S, Tonelli C, Paz-Ares J, Weisshaar B (1998) Towards functional characterisation of the members of the R2R3-MYB gene family from Arabidopsis thaliana. Plant J 16:263–276

    Article  CAS  PubMed  Google Scholar 

  • Lee MM, Schiefelbein J (1999) WEREWOLF, a MYB related protein in Arabidopsis, is a position dependent regulator of epidermal cell patterning. Cell 99:473–483

    Article  CAS  PubMed  Google Scholar 

  • Lee MW, Qi M, Yang Y (2001) A novel jasmonic acid-inducible rice MYB gene associates with fungal infection and host cell death. Mol Plant Microbe Interact 14:527–535

    Article  CAS  PubMed  Google Scholar 

  • Lee DK et al (2009) Lateral organ fusion1 and lateral organ fusion2 function in lateral organ separation and axillary meristem formation in Arabidopsis. Development 136:2423–2432

    Google Scholar 

  • Lepiniec L, Debeaujon I, Routaboul JM, Baudry A, Pourcel L, Nesi N, Caboche M (2006) Genetics and biochemistry of seed flavonoids. Annu Rev Plant Biol 57:405–430

    Article  CAS  PubMed  Google Scholar 

  • Jigang L et al (2006) A subgroup of MYB transcription factor genes undergoes highly conserved alternative splicing in Arabidopsis and rice. J Exp Bot 57:1263–1273

    Article  CAS  Google Scholar 

  • Li L et al (2009) Arabidopsis MYB30 is a direct target of BES1 and cooperates with BES1 to regulate brassinosteroid-induced gene expression. Plant J 58:275–286

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Liang YK et al (2005) AtMYB61, an R2R3-MYB transcription factor controlling stomatal aperture in Arabidopsis thaliana. Curr Biol 15:1201–1206

    Article  CAS  PubMed  Google Scholar 

  • Liao Y, Zou HF, Wang HW, Zhang WK, Ma B, Zhang JS (2008) Soybean GmMYB76, GmMYB92, and GmMYB177 genes confer stress tolerance in transgenic Arabidopsis plants. Cell Res 18:1047–1060

    Article  CAS  PubMed  Google Scholar 

  • Lin-Wang K, Bolitho K, Grafton K, Kortstee A, Karunairetnam S, McGhie TK, Espley RV, Hellens RP, Allan AC (2010) An R2R3 MYB transcription factor associated with regulation of the anthocyanin biosynthetic pathway in Rosaceae. BMC Plant Biol 10:50–66

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Lippold F, Sanchez DH, Musialak M, Schlereth A, Scheible WR, Hincha DK, Udvardi MK (2009) AtMyb41 regulates transcriptional and metabolic responses to osmotic stress in Arabidopsis. Plant Physiol 149:1761–1772

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lipsick JS (1996) One billion years of Myb. Oncogene 13:223–235

    CAS  PubMed  Google Scholar 

  • Liu L, Du H, Tang XF, Wu YM, Huang YB, Tang YX (2008) The roles of MYB transcription factors on plant defense responses and its molecular mechanism. Hereditas 30:1265–1271

    Article  CAS  PubMed  Google Scholar 

  • Liu R, Lü B, Wang X, Zhang C, Zhang S, Qian J, Chen L, Shi H, Dong H (2010) Thirty-seven transcription factor genes differentially respond to a hairpin protein and affect resistance to the green peach aphid in Arabidopsis. J Biosci 35:435–450. doi:10.1007/s12038-010-0049-8

    Article  CAS  PubMed  Google Scholar 

  • Lu SX, Knowles SM, Andronis C, Ong MS, Tobin EM (2009) Circadian clock associated1 and late elongated hypocotyl function synergistically in the circadian clock of Arabidopsis. Plant Physiol 150:834–843

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ma Q et al (2009) Enhanced tolerance to chilling stress in OsMYB3R-2 transgenic rice is mediated by alteration in cell cycle and ectopic expression of stress genes. Plant Physiol 150:244–256

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Maeda K, Kimura S, Demura T, Takeda J, Ozeki Y (2005) DcMYB1 acts as a transcriptional activator of the carrot phenylalanine ammonia-lyase gene (DcPAL1) in response to elicitor treatment, UV-B irradiation and the dilution effect. Plant Mol Biol 59:739–752

    Article  CAS  PubMed  Google Scholar 

  • Mandaokar A, Browse J (2009) MYB108 acts together with MYB24 to regulate jasmonate-mediated stamen maturation in Arabidopsis. Plant Physiol 149:851–862

    Google Scholar 

  • Mandaokar A et al (2006) Transcriptional regulators of stamen development in Arabidopsis identified by transcriptional profiling. Plant J 46:984–1008

    Article  CAS  PubMed  Google Scholar 

  • Martin C, Paz-Ares J (1997) MYB transcription factors in plants. Trends Genet 13:67–73

    Article  CAS  PubMed  Google Scholar 

  • Mengiste T, Chen X, Salmeron J, Dietrich R (2003) The BOTRYTIS SUSCEPTIBLE1 gene encodes an R2R3MYB transcription factor protein that is required for biotic and abiotic stress responses in Arabidopsis. Plant Cell 15:2551–2565

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Meshi T, Iwabuchi M (1995) Plant transcription factors. Plant Cell Physiol 36:1405–1420

    CAS  PubMed  Google Scholar 

  • Millar AA, Gubler F (2005) The Arabidopsis GAMYB-like genes, MYB33 and MYB65, are microRNA-regulated genes that redundantly facilitate anther development. Plant Cell 17:705–721

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Morita Y, Saitoh M, Hoshino A, Nitasaka E, Iida S (2006) Isolation of cDNAs for R2R3-MYB, bHLH and WDR transcriptional regulators and identification of c and ca mutations conferring white flowers in the Japanese Morning Glory. Plant Cell Physiol 47:457–470

    Article  CAS  PubMed  Google Scholar 

  • Moyano E, Martinez-Garcia JF, Martin C (1996) Apparent redundancy in myb gene function provides gearing for the control of flavonoid biosynthesis in Antirrhinum flowers. Plant Cell 8:1519–1532

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mu RL et al (2009) An R2R3-type transcription factor gene AtMYB59 regulates root growth and cell cycle progression in Arabidopsis. Cell Res 19:1291–1304

    Google Scholar 

  • Murray F, Kalla R, Jacobsen J, Gubler F (2003) A role for HvGMYB in anther development. Plant J 33:481–491

    Article  CAS  PubMed  Google Scholar 

  • Narasuka Y, Nakashima K, Shinwari ZK, Sakuma Y, Furihata T, Abe H, Narusaka M, Shinozaki K, Yamaguchi-Shinozaki K (2003) Interaction between two cis-acting elements, ABRE and DRE, in ABA-dependent expression of Arabidopsis rd29A gene in response to dehydration and high-salinity stresses. Plant J 34:137–148

    Google Scholar 

  • Nesi N, Jond C, Debeaujon I, Caboche M (2001) The Arabidopsis TT2 gene encodes an R2R3 MYB domain protein that acts as a key determinant for proanthocyanidin accumulation in developing seed. Plant Cell 13:2311–2322

    Google Scholar 

  • Newman LJ et al (2004) Involvement of the R2R3-MYB, AtMYB61, in the ectopic lignification and dark-photomorphogenic components of the det3 mutant phenotype. Plant J 37:239–250

    Article  CAS  PubMed  Google Scholar 

  • Noda KI, Glover BJ, Linstead P, Martin C (1994) Flower colour intensity depends on specialized cell shape controlled by a Myb-related transcription factor. Nature 369:661–664

    Article  CAS  PubMed  Google Scholar 

  • Ogata K et al (1996) The cavity in the hydrophobic core of Myb DNA binding domain is reserved for DNA recognition and trans-activation. Nat Struct Biol 3:178–818

    Article  CAS  PubMed  Google Scholar 

  • Oppenheimer DG, Hertman PL, Sivakumaran S, Esch J (1991) A myb gene required for leaf trichome differentiation in Arabidopsis is expressed in stipules. Cell 67:483–493

    Google Scholar 

  • Park JS et al (2008) Arabidopsis R2R3-MYB transcription factor AtMYB60 functions as a transcriptional repressor of anthocyanin biosynthesis in lettuce (Lactuca sativa). Plant Cell Rep 27:985–994

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pasquali G et al (2008) OsMYB4 expression improves adaptive responses to drought and cold stress in transgenic apples. Plant Cell Rep 27:1677–1686

    Article  CAS  PubMed  Google Scholar 

  • Paz-Ares J, Ghosal D, Wienand U, Peterson PA, Saedler H (1987) The regulatory c1 locus of Zea mays encodes a protein with homology to myb proto-ncogene products and with structural similarities to transcriptional activators. EMBO J 6:3553–3558

    CAS  PubMed  PubMed Central  Google Scholar 

  • Penfield S et al (2001) MYB61 is required for mucilage deposition and extrusion in the Arabidopsis seed coat. Plant Cell 13:2777–2791

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pesch M, Hulskamp M (2009) One, two, three.models for trichome patterning in Arabidopsis. Curr Opin Plant Biol 12:587–592

    Article  CAS  PubMed  Google Scholar 

  • Prabu G, Prasad DT (2012) Functional characterization of sugarcane MYB transcription factor gene promoter (PScMYBAS1) in response to abiotic stresses and hormones. Plant Cell Rep 4:661–669. doi:10.1007/s00299-011-1183-y

    Article  CAS  Google Scholar 

  • Prabu GR, Theertha PD (2011) Structure of DNA binding Myb transcription factor protein (SCMYBAS1-3) from sugarcane-threading and AB initio modelling. J Phytol 3:77–82

    CAS  Google Scholar 

  • Punwani JA et al (2008) The MYB98 subcircuit of the synergid gene regulatory network includes genes directly and indirectly regulated by MYB98. Plant J 55:406–414

    Article  CAS  PubMed  Google Scholar 

  • Quaedvlieg N, Dockx J, Keultjes G, Kock P, Wilmering J, Weisbeek P, Smeekens S (1996) Identification of a light regulated MYB gene from an Arabidopsis transcription factor gene collection. Plant Mol Biol 32:987–993

    Article  CAS  PubMed  Google Scholar 

  • Quattrocchio F, Wing JF, Leppen HTC, Mol JNM, Koes RE (1993) Regulatory genes controlling anthocyanin pigmentation are conserved among plant species and have distinct set of target genes. Plant Cell 5:1497–1512

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rabinowicz PD, Braun EL, Wolfe AD, Bowen B, Grotewold I (1999) Maize R2R3 Myb genes: sequence analysis reveals amplification in the higher plants. Genetics 153:427–444

  • Raffaele S, Rivas S, Roby D (2006) An essential role for salicylic acid in AtMYB30-mediated control of the hypersensitive cell death program in Arabidopsis. FEBS Lett 580:3498–3504

    Article  CAS  PubMed  Google Scholar 

  • Raffaele S et al (2008) A MYB transcription factor regulates very-long-chain fatty acid biosynthesis for activation of t he hypersensitive cell death Response in Arabidopsis. Plant Cell 20:752–767

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Reyes JL, Chua NH (2007) ABA induction of miR159 controls transcript levels of two MYB factors during Arabidopsis seed germination. Plant J 49:592–606

    Article  CAS  PubMed  Google Scholar 

  • Riechmann JL, Heard J, Martin G, Reuber L, Jiang CZ, Keddie J, Adam L, Pineda O, Ratcliffe OJ, Samara RR, Creelman R, Pilgrim M, Broun P, Zhang JZ, Chandahari D, Sherman BK, Yu CL (2000) Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science 290:2105–2110

    Article  CAS  PubMed  Google Scholar 

  • Rosinski JA, Atchley WR (1998) Molecular evolution of the Myb family of transcription factors: evidence for polyphyletic origin. J Mol Evol 46:74–83

    Article  CAS  PubMed  Google Scholar 

  • Rouached H, Secco D, Arpat B, Poirier Y (2011) The transcription factor PHR1 plays a key role in the regulation of sulfate shoot-to-root flux upon phosphate starvation in Arabidopsis. BMC Plant Biol 11:19. doi:10.1186/1471-2229-11-19

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rubio V, Linhares F, Solano R, Martín AC, Iglesias J, Leyva A, Paz-Ares J (2001) A conserved MYB transcription factor involved in phosphate starvation signaling both in vascular plants and in unicellular algae. Genes Dev 15:2122–2133

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Schaffer R, Ramsay N, Samach A, Corden S, Putterill J, Carre IA, Coupland G (1998) The late elongated hypocotyl mutation of Arabidopsis disrupts circadian rhythms and the photoperiodic control of flowering. Cell 93:1219–1229

    Google Scholar 

  • Schaffer R, Landgraf J, Accerbi M, Simon V, Larson M, Wisman E (2001) Microarray analysis of diurnal and circadian-regulated genes in Arabidopsis. Plant Cell 13:113–123

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Scoville AG, Barnett LL, Roels SB, Kelly JK, Hileman LC (2011) Differential regulation of a MYB transcription factor is correlated with transgenerational epigenetic inheritance of trichome density in Mimulus guttatus. New Phytol 191(1):251–263

    Google Scholar 

  • Segarra G, Van der Ent S, Trillas I, Pieterse CMJ (2009) MYB72, a node of convergence in induced systemic resistance triggered by a fungal and a bacterial beneficial Microbe. Plant Biol 11:90–96

    Article  CAS  PubMed  Google Scholar 

  • Seo PJ, Park CM (2009) Auxin homeostasis during lateral root development under drought condition. Plant Signal Behav 4:1002–1004

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Seo PJ, Park CM (2010) MYB96-mediated abscisic acid signals induce pathogen resistance response by promoting salicylic acid biosynthesis in Arabidopsis. New Phytol 186:471–483

    Google Scholar 

  • Seo PJ et al (2009) The MYB96 transcription factor mediates abscisic acid signaling during drought stress response in Arabidopsis. Plant Physiol 151:275–289

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Seo PJ, Lee SB, Suh MC, Park MJ, Go YS, Park CM (2011) The MYB96 Transcription factor regulates cuticular wax biosynthesis under drought conditions in Arabidopsis. Plant Cell 23:1138–1152

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sharma P, Kumar H, Supriya, Kumar S, Yadav NR, Pradeep, Yadav RC, Singh D (2010) Comparative myb gene expression in Brassica species under drought stress through semi-quantitative RT-PCR. Cruciferae Newslett 29:23–25

    Google Scholar 

  • Shin B, Choi G, Yi H, Yang S, Cho I, Kim J, Lee S, Paek NC, Kim JH, Song PS, Choi G (2002) AtMYB21, a gene encoding a flower-specific transcription factor, is regulated by COP1. Plant J 30:23–32

    Article  CAS  PubMed  Google Scholar 

  • Shin R et al (2007) The Arabidopsis transcription factor MYB77 modulates auxin signal transduction. Plant Cell 19:2440–2453

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Shinozaki K, Yamaguchi-Shinozaki K (2000) Molecular responses to dehydration and low temperature: differences and cross-talk between two stress signaling pathways. Curr Opin Plant Biol 3:217–223

    Article  CAS  PubMed  Google Scholar 

  • Shinozaki K, Yamaguchi-Shinozaki K, Urao OT, Koizumi M (1992) Nucleotide sequence of a gene from Arabidopsis thaliana encoding a myb homologue. Plant Mol Biol 19:493–499

  • Solano R, Nieto C, Avila J, Canas L, Diaz I, Paz-Ares J (1995) Dual DNA binding specificity of a petal epidermis-specific MYB transcription factor (MYBPh3) from Petunia hybrida. EMBO J 14:1773–1784

    CAS  PubMed  PubMed Central  Google Scholar 

  • Song S, Qi T, Huang H, Ren Q, Wu D, Chang C, Peng W, Liu Y, Peng J, Xie D (2011) The Jasmonate-ZIM domain proteins interact with the R2R3-MYB transcription factors MYB21 and MYB24 to affect jasmonate-regulated stamen development in Arabidopsis. Plant Cell 23:1000–1013

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Steiner-Lange S, Unte US, Eckstein L, Yang C, Wilson ZA, Schmelzer E, Dekker K, Saedler H (2003) Disruption of Arabidopsis thaliana MYB26 results in male sterility due to non-dehiscent anthers. Plant J 34:519–528

    Article  CAS  PubMed  Google Scholar 

  • Stracke R, Werber M, Weisshaar B (2001) The R2R3–MYB gene family in Arabidopsis thaliana. Curr Opin Plant Biol 4:447–456

    Google Scholar 

  • Stracke R, Ishihara H, Huep G, Barsch A, Mehrtens F, Niehaus K, Weisshaar B (2007) Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling. Plant J 50:660–677

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Stracke R, Favory JJ, Gruber H, Bartelniewoehner L, Bartels S, Binkert M, Funk M, Weisshaar B, Ulm R (2010) The Arabidopsis bZIP transcription factor HY5 regulates expression of the PFG1/MYB12 gene in response to light and ultraviolet-B radiation. Plant Cell Environ 33:88–103

    CAS  PubMed  Google Scholar 

  • Su CF et al (2010) A novel MYBS3-dependent pathway confers cold tolerance in rice. Plant Physiol 153:145–158

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Suo J, Liang X, Pu L, Zhang Y, Xue Y (2003) Identification of GhMYB109 encoding a R2R3MYB transcription factor that expressed specifically in fiber initials and elongating fibers of cotton (Gossypium hirsutum L.). Biochem Biophys Acta 1630:25–34

    CAS  PubMed  Google Scholar 

  • Supriya YNR, Yadav RC, Singh D (2006) Isolation of biologically active RNA for generating myb transcription factor cDNAs in Brassica species. Brassica 8:95–98

    CAS  Google Scholar 

  • Takahashi R, Yamagishi N, Yoshika N (2013) A MYB transcription factor controls flower color in soybean. J Hered 104(1):149–153

    Google Scholar 

  • Tamagnone L, Merida A, Parr A, Mackay S, Culianez-Macia FA, Roberts K, Martin C (1998) The AmMYB308 and AmMYB330 transcription factors from Antirrhinum regulate phenylpropanoid and lignin biosynthesis in transgenic tobacco. Plant Cell 10:135–154

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Urao T, Yamaguchi-Shinozaki K, Urao S, Shinozaki K (1993) An Arabidopsis myb homolog is induced by dehydration stress and its gene product binds to the conserved MYB recognition sequence. Plant Cell 5:1529–1539

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Van der Ent S et al (2008) MYB72 is required in early signaling steps of Rhizobacteria-induced systemic resistance in Arabidopsis. Plant Physiol 146:1293–1304

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Vannini C, Locatelli F, Bracale M, Magnani E, Marsoni M, Osnato M, Mattana M, Baldoni E, Coraggio I (2004) Overexpression of the rice OsMYB4 gene increases chilling and freezing tolerance of Arabidopsis thaliana plants. Plant J 37:115–127

    Article  CAS  PubMed  Google Scholar 

  • Verdier J et al (2012) MtPAR MYB transcription factor acts as an on switch for proanthocyanidin biosynthesis in Medicago truncatula. PNAS 109(5):1766–1771

    Google Scholar 

  • Wang X et al (2008) Overexpression of PGA37/MYB118 and MYB115 promotes vegetative-to-embryonic transition in Arabidopsis. Cell Res 19:224–235

    Article  CAS  Google Scholar 

  • Wang S, Barron C, Schiefelbein J, Chen JG (2010) Distinct relationships between GLABRA2 and single-repeat R3 MYB transcription factors in the regulation of trichome and root hair patterning in Arabidopsis. New Phytol 185:387–400

    Article  CAS  PubMed  Google Scholar 

  • Wilkins O, Nahal H, Foong J, Provart NJ, Campbell MM (2009) Expansion and diversification of the Populus R2R3–MYB family of transcription factors. Plant Physiol 149:981–993

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Woodger FJ, Gubler F, Pogson BJ, Jacobsen JV (2003) A MAK-like kinase is a repressor of GAMYB in barley aleurone. Plant J 33:707–717

    Article  CAS  PubMed  Google Scholar 

  • Xie Z, Lee EK, Lucas JR, Morohashi K, Li D, Murray JAH, Sack FD, Grotewold E (2010) Plant Cell 22:2306–2321

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Xiong C, Zhonghe M, Eric L (1997) DNA binding properties, genomic organization and expression pattern of TGA6, a new member of the TGA family of bZIP transcription factors in Arabidopsis thaliana. Plant Mol Biol 34:403–415

    Article  Google Scholar 

  • Yang Y, Klessig DF (1996) Isolation and characterization of a tobacco mosaic virus-inducible myb oncogene homolog from tobacco. Proc Natl Acad Sci 93:14972–14977

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yang S, Sweetman JP, Amirsadeghi S, Barghchi M, Huttly AK, Chung WI, Twell D (2001) Novel anther-specific myb genes from tobacco as putative regulators of phenylalanine ammonia-lyase expression. Plant Physiol 126:1738–1753

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yang C et al (2007) Arabidopsis MYB26/MALE STERILE35 regulates secondary thickening in the endothecium and is essential for anther dehiscence. Plant Cell 19:534–548

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yang A, Xiaoyan Dai X, Zhang WH (2012) A R2R3-type MYB gene, OsMYB2, is involved in salt, cold, and dehydration tolerance in rice. J Exp Bot 63(7):2541–2556

    Google Scholar 

  • Yanhui C et al (2006) The MYB transcriptionfactor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family. Plant Mol Biol 60:107–124

    Article  PubMed  CAS  Google Scholar 

  • Yi J, Derynck MR, Li X, Telmer P, Marsolais F, Dhaubhadel S (2010) A single-repeat MYB transcription factor, GmMYB176, regulates CHS8 gene expression and affects isoflavonoid biosynthesis in soybean. Plant J 62:1019–1034

    CAS  PubMed  Google Scholar 

  • Yu EY, Kim SE, Kim JH, Ko JH, Cho MH, Chung IK (2000) Sequence-specific DNA recognition by the Myb-like domain of plant telomeric protein RTBP1. J Biol Chem 275:24208–24214

    Article  CAS  PubMed  Google Scholar 

  • Zhang Y et al (2009) Characterization of Arabidopsis MYB transcription factor gene AtMYB17 and its possible regulation by LEAFY and AGL15. J Genet Genomics 36:99–107

    Article  PubMed  CAS  Google Scholar 

  • Zhang X, Ju HW, Chung MS, Huang P, Ahn SJ, Kim CS (2011) The R-R-type MYB-like transcription factor, AtMYBL, is involved in promoting leaf senescence and modulates an abiotic stress response in Arabidopsis. Plant Cell Physiol 52:138–148

    Article  CAS  PubMed  Google Scholar 

  • Zhong R et al (2007) The MYB46 transcription factor is a direct target of SND1 and regulates secondary wall biosynthesis in Arabidopsis. Plant Cell 19:2776–2792

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zhong R et al (2008) A battery of transcription factors involved in the regulation of secondary cell wall biosynthesis in Arabidopsis. Plant Cell 20:2763–2782

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zhou J et al (2009) MYB58 and MYB63 are transcriptional activators of the lignin biosynthetic pathway during secondary cell wall formation in Arabidopsis. Plant Cell 21:248–266

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgments

The authors (RCY and NRY) acknowledge the financial assistance provided by DBT, Govt. of India.

Author information

Authors and Affiliations

  1. Department of Molecular Biology and Biotechnology, CCS Haryana Agricultural University, Hisar, 125004, India

    Supriya Ambawat, Poonam Sharma, Neelam R. Yadav & Ram C. Yadav

Authors
  1. Supriya Ambawat
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Poonam Sharma
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Neelam R. Yadav
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ram C. Yadav
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Neelam R. Yadav.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ambawat, S., Sharma, P., Yadav, N.R. et al. MYB transcription factor genes as regulators for plant responses: an overview. Physiol Mol Biol Plants 19, 307–321 (2013). https://doi.org/10.1007/s12298-013-0179-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12298-013-0179-1

Keywords

Search

Navigation