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Phototherapie der entzündlichen Akne

Light-based inflammatory acne treatments

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Zusammenfassung

Verfahren der Phototherapie könnten sich als neue Ansätze der Aknebehandlung etablieren, die das Risiko bakterieller Resistenzen nicht steigern und bei günstigem Sicherheitsprofil potenziell wirksam sind. Nach aktuellen Studiendaten bewirkt die photodynamische Therapie eine Verringerung entzündlicher Läsionen und eine deutliche Verbesserung der Akne. Allerdings besteht keine Einigkeit über die optimale Durchführung im Rahmen der Aknebehandlung. Neben der topisch angewendeten photodynamischen Therapie wurden die Intense-pulsed-light-Methode (hochenergetische Lichtblitze), gepulste Farbstofflaser, Kaliumtitanylphosphatlaser, Infrarotdiodenlaser und polychromatische Lichtquellen (Rotlicht, Rot-blau-Licht) als alternative Verfahren eingeführt. Da gut konzipierte Studien zur Wirksamkeitsprüfung im Vergleich zu traditionellen Pharmakotherapien fehlen und die Methoden nicht standardisiert sind, sollten Verfahren wie Laser‑, Intense-pulsed-light- und photodynamische Therapie gegenwärtig nicht als Erstlinienbehandlung der entzündlichen Akne betrachtet werden.

Abstract

Light-based acne treatments may represent a new emerging treatment for acne that does not increase the risk of bacterial resistance and they may be potentially effective with a favorable safety profile. Current data show that photodynamic therapy reduces inflammatory lesions and significantly improves acne. However, there is no consensus on the optimal implementation in the treatment of acne. In addition to topically applied photodynamic therapy, intense pulsed light, pulsed dye lasers, potassium-titanyl-phosphate lasers, infrared diode lasers, broad-spectrum continuous-wave light sources (red light, blue–red light) have been introduced as alternative treatments. Since well-designed studies to evaluate their efficacy versus traditional medical therapies are lacking and standardized regimens have not been agreed upon, procedures including laser, intense pulsed light, and photodynamic therapy should currently not be considered first-line treatment for inflammatory acne.

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Author information

Authors and Affiliations

  1. Abteilung für Pädiatrische Dermatologie, Colentina-Krankenhaus, 19–21 Stefan cel Mare Av., Bukarest, Rumänien

    C. Salavastru

  2. Medizinische und Pharmazeutische Universität Carol Davila, Bukarest, Rumänien

    C. Salavastru,  G. S. Tiplica &  K. Fritz

  3. Klinik für Dermatologie II, Colentina-Krankenhaus, Bukarest, Rumänien

    G. S. Tiplica

  4. Klinik für Dermatologie, Medizinische und Pharmazeutische Universität Grigore T. Popa, Iaşi, Rumänien

    D. E. Branisteanu

  5. Hautärzte- und Laserzentrum Landau (Pfalz), Landau, Deutschland

    K. Fritz

Authors
  1. C. Salavastru
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  3. D. E. Branisteanu
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  4. K. Fritz
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Corresponding author

Correspondence to C. Salavastru.

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Interessenkonflikt

C. Salavastru, G.S. Tiplica, D.E. Branisteanu und K. Fritz geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Salavastru, C., Tiplica, G.S., Branisteanu, D.E. et al. Phototherapie der entzündlichen Akne. Hautarzt 69, 27–34 (2018). https://doi.org/10.1007/s00105-017-4099-9

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  • DOI: https://doi.org/10.1007/s00105-017-4099-9

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