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Challenges in dosimetry of particle beams with ultra-high pulse dose rates / Romano, F (INFN, Catania ; Teddington, Natl. Phys. Lab) ; Subiel, A (Teddington, Natl. Phys. Lab) ; McManus, M (Teddington, Natl. Phys. Lab) ; Lee, N D (Teddington, Natl. Phys. Lab) ; Palmans, H (Teddington, Natl. Phys. Lab ; Unlisted, AT) ; Thomas, R (Teddington, Natl. Phys. Lab) ; McCallum, S (Teddington, Natl. Phys. Lab ; Queen's U., Belfast) ; Milluzzo, G (Queen's U., Belfast) ; Borghesi, M (Queen's U., Belfast) ; McIlvenny, A (Queen's U., Belfast) et al.
Recent results from pre-clinical studies investigating the so-called FLASH effect suggest that the ultrahigh pulse dose rates (UHPDR) of this modality reduces normal tissue damage whilst preserving tumour response, when compared with conventional radiotherapy (RT). FLASH-RT is characterized by average dose rates of dozens of Gy/s instead of only a few Gy/min. [...]
2020 - 5 p. - Published in : J. Phys.: Conf. Ser. 1662 (2020) 012028 Fulltext: PDF;

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The challenge of ionisation chamber dosimetry in ultra-short pulsed high dose-rate Very High Energy Electron beams / McManus, M (Teddington, Natl. Phys. Lab ; U. Coll. London) ; Romano, F (INFN, Catania ; Teddington, Natl. Phys. Lab) ; Lee, N D (Teddington, Natl. Phys. Lab) ; Farabolini, W (CERN ; IRFU, Saclay) ; Gilardi, A (CERN) ; Royle, G (U. Coll. London) ; Palmans, H (Medaustron, Vienna ; Teddington, Natl. Phys. Lab) ; Subiel, A (Teddington, Natl. Phys. Lab)
High dose-rate radiotherapy, known as FLASH, has been shown to increase the differential response between healthy and tumour tissue. Moreover, Very High Energy Electrons (VHEEs) provide more favourable dose distributions than conventional radiotherapy electron and photon beams. [...]
2020 - 11 p. - Published in : Sci. Rep. 10 (2020) 9089 Fulltext: PDF;

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