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A high-resolution large-area detector for quality assurance in radiotherapy
/ Oliveira, Andreia Maia (CERN ; Bern U., LHEP ; MedAustron) ; B Akkerman, Hylke ; Braccini, Saverio (Bern U., LHEP) ; van Breemen, Albert J J M ; H Gelinck, Gerwin (Unlisted, NL) ; Heracleous, Natalie (CERN ; Ecole Polytechnique, Lausanne) ; Leidner, Johannes (CERN ; Lausanne U.) ; Murtas, Fabrizio (CERN ; LNF, Dafne Light) ; Peeters, Bart ; Silari, Marco (CERN)
Hadron therapy is an advanced radiation modality for treating cancer, which currently uses protons and carbon ions. Hadrons allow for a highly conformal dose distribution to the tumour, minimising the detrimental side-effects due to radiation received by healthy tissues. [...]
2024 - 12 p.
- Published in : Sci. Rep. 14 (2024) 10637
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A Large Area GEMPix detector for treatment plan verification in hadron therapy
/ Oliveira, Andreia Maia (CERN ; U. Bern, AEC) ; Akkerman, Hylke B ; Braccini, Saverio (U. Bern, AEC) ; van Breemen, Albert J J M ; Manzano, Lucia Gallego (CERN) ; Heracleous, Natalie (CERN) ; Katsouras, Ilias (ASML, Veldhoven) ; Leidner, Johannes (CERN) ; Murtas, Fabrizio (CERN ; LNF, Dafne Light) ; Peeters, Bart et al.
Quality Assurance in hadron therapy is crucial to ensure a safe and accurate dose delivery to the patients. This requires fast and reliable detectors with high spatial resolution. [...]
2022 - 7 p.
- Published in : J. Phys. : Conf. Ser. 2374 (2022) 012177
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In : International Conference on Technology and Instrumentation in Particle Physics (TIPP 2021), Online, Canada, 24 - 29 May 2021, pp.012177
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Eurados Rem-counter Intercomparison at Maastro Proton Therapy Centre: Comparison With Literature Data
/ Zorloni, Gabriele (CERN) ; Bosmans, Geert (Maastricht U.) ; Brall, Thomas (HZDR, Dresden) ; Caresana, Marco (INFN, Milan ; Milan U.) ; De Saint-Hubert, Marijke (SCK-CEN, Mol) ; Domingo, Carles (Barcelona, IFAE ; Barcelona, Autonoma U.) ; Ferrante, Christian (INFN, Milan ; Milan U.) ; Ferrulli, Francesca (CERN ; U. Caen (main)) ; Kopec, Renata (Cracow, INP) ; Leidner, Johannes (CERN) et al.
The Maastro Proton Therapy Centre is the first European facility housing the Mevion S250i Hyperscan synchrocyclotron. The proximity of the accelerator to the patient, the presence of an active pencil beam delivery system downstream of a passive energy degrader and the pulsed structure of the beam make the Mevion stray neutron field unique amongst proton therapy facilities. [...]
2022 - 5 p.
- Published in : Radiat. Prot. Dosim. 198 (2022) 1471-1475
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A vacuum chamber for operation of a GEM-based detector in sealed-mode and at low pressure for LET measurements
/ Leidner, Johannes (CERN) ; Heracleous, Natalie (CERN) ; Kołodziej, Barbara (CERN ; Jagiellonian U.) ; Murtas, Fabrizio (CERN ; LNF, Dafne Light) ; Scapini, Alessandro (CERN ; Milan, Polytech.) ; Silari, Marco (CERN) ; Thomsen, Frederik (CERN ; Aarhus U. (main))
The GEMTEQ is a gaseous detector with Gas Electron Multipliers for signal amplification and Timepix ASICS as highly pixelated readout. It is based on the GEMPix detector and designed for microdosimetry. [...]
2022 - 11 p.
In : Vienna Conference on Instrumentation, Online, Online, 21 - 25 Feb 2022, pp.167365
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Joint EURADOS WG9-WG11 rem-counter intercomparison in a Mevion S250i proton therapy facility with Hyperscan pulsed synchrocyclotron
/ Zorloni, Gabriele (CERN) ; Bosmans, Geert (Maastricht U.) ; Brall, Thomas (Helmholtz Zentrum Munchen, Neuherberg) ; Caresana, Marco (U. Milan (main)) ; De Saint-Hubert, Marijke (SCK-CEN, Mol) ; Domingo, Carles (Barcelona, Autonoma U.) ; Ferrante, Christian (U. Milan (main)) ; Ferrulli, Francesca (CERN ; U. Caen (main)) ; Kopec, Renata (Cracow, INP) ; Leidner, Johannes (CERN) et al.
Objective. Proton therapy is gaining popularity because of the improved dose delivery over conventional radiation therapy. [...]
2022 - 16 p.
- Published in : Phys. Med. Biol. 67 (2022) 075005
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Characterization with X-rays of a Large-Area GEMPix Detector with Optical Readout for QA in Hadron Therapy
/ Oliveira, Andreia Maia (CERN ; Bern U., LHEP) ; Akkerman, Hylke B (Unlisted, NL) ; Braccini, Saverio (Bern U., LHEP) ; van Breemen, Albert J J M (Unlisted, NL) ; Manzano, Lucia Gallego (CERN ; Lausanne U.) ; Heracleous, Natalie (CERN ; Lausanne U.) ; Katsouras, Ilias (Unlisted, NL ; ASML, Veldhoven) ; Leidner, Johannes (CERN) ; Murtas, Fabrizio (CERN ; Frascati) ; Peeters, Bart (Unlisted, NL) et al.
Quality Assurance (QA) in hadron therapy is crucial to ensure safe and accurate dose delivery to patients. This can be achieved with fast, reliable and high-resolution detectors. [...]
2021 - 20 p.
- Published in : Appl. Sciences 11 (2021) 6459
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Medical Applications of the GEMPix
/ Leidner, Johannes (CERN) ; Murtas, Fabrizio (CERN ; LNF, Dafne Light) ; Silari, Marco (CERN)
The GEMPix is a small gaseous detector with a highly pixelated readout, consisting of a drift region, three Gas Electron Multipliers (GEMs) for signal amplification, and four Timepix ASICs with 55 µm pixel pitch and a total of 262,144 pixels. A continuous flow of a gas mixture such as Ar:CO2:CF4, Ar:CO2 or propane-based tissue equivalent gas is supplied externally at a rate of 5 L/h. [...]
2021 - 20 p.
- Published in : Appl. Sciences 11 (2021) 440
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Radiation-induced effects in glass windows for optical readout GEM-based detectors
/ Oliveira, A. Maia (CERN ; Bern U., LHEP) ; Braccini, S. (Bern U., LHEP) ; Casolaro, P. (Bern U., LHEP) ; Heracleous, N. (CERN) ; Leidner, J. (CERN) ; Mateu, I. (Bern U., LHEP) ; Murtas, F. (CERN ; Frascati) ; Silari, M. (CERN)
In this paper we present irradiation measurements performed to select a transparent anode substrate that best meets the requirements of an optical readout for a novel detector, the LaGEMPix. The modification of the optical properties of the material due to proton irradiation were studied in soda-lime, fused quartz and fused silica glasses coated with an Indium Tin Oxide layer. [...]
arXiv:2106.04645.-
2021-07-19 - 14 p.
- Published in : JINST 16 (2021) T07009
Fulltext: document - PDF; 2106.04645 - PDF;
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