001227949 001__ 1227949
001227949 003__ SzGeCERN
001227949 005__ 20240202044732.0
001227949 0248_ $$aoai:cds.cern.ch:1227949$$pcerncds:FULLTEXT$$pcerncds:CERN:FULLTEXT$$pcerncds:CERN
001227949 035__ $$9arXiv$$aoai:arXiv.org:0912.1709
001227949 035__ $$9SPIRES$$a8491569
001227949 035__ $$9SPIRES$$a8491569
001227949 035__ $$9Inspire$$a839443
001227949 037__ $$9arXiv$$aarXiv:0912.1709$$cphysics.comp-ph
001227949 041__ $$aeng
001227949 100__ $$aGargioni, Elisabetta$$uEppendorf, U. Hospital
001227949 245__ $$aRe-engineering a nanodosimetry Monte Carlo code into Geant4: software design and first results
001227949 260__ $$c2009
001227949 269__ $$c10 Dec 2009
001227949 300__ $$a4 p
001227949 500__ $$aComments: 4 pages, 2 figures and images, to appear in proceedings of the Nuclear Science Symposium and Medical Imaging Conference 2009, Orlando
001227949 520__ $$9IEEE$$aMicrobeam Radiation Therapy (MRT) is an innovative experimental technique potentially able to overcome the limitations of conventional radiotherapy for infantile brain tumors. Its effectiveness seems to be related to the ability of normal tissues to tolerate a very high radiation dose in small volumes, resulting in the preservation of the tissues' architecture. The effectiveness of MRT is well represented by peak-to-valley dose ratios (PVDRs), which are one of the crucial parameters associated with the outcome of the treatment. We present Geant4 Monte Carlo calculations of the dose distribution deposited by planar polarized microbeams with micrometric resolution. The simulation of the beam polarization, made possible by different libraries included in Geant4, is a crucial step in enhancing the comparability of experimental data and simulation results.
001227949 520__ $$9arXiv$$aA set of physics models for nanodosimetry simulation is being re-engineered for use in Geant4-based simulations. This extension of Geant4 capabilities is part of a larger scale R&D project for multi-scale simulation involving adaptable, co-working condensed and discrete transport schemes. The project in progress reengineers the physics modeling capabilities associated with an existing FORTRAN track-structure code for nanodosimetry into a software design suitable to collaborate with an object oriented simulation kernel. The first experience and results of the ongoing re-engineering process are presented.
001227949 595__ $$aLANL EDS
001227949 65017 $$2arXiv$$aOther Fields of Physics
001227949 695__ $$9LANL EDS$$aphysics.comp-ph
001227949 690C_ $$aPREPRINT
001227949 690C_ $$aCERN
001227949 700__ $$aGrichine, Vladimir$$uLebedev Inst.$$uCERN
001227949 700__ $$aPia, Maria Grazia$$uINFN, Genoa
001227949 773__ $$01312815$$wC09-10-25
001227949 8564_ $$uhttp://arxiv.org/pdf/0912.1709.pdf$$yPreprint
001227949 8564_ $$82434047$$s385360$$uhttp://cds.cern.ch/record/1227949/files/arXiv:0912.1709.pdf
001227949 8564_ $$82434046$$s71436$$uhttp://cds.cern.ch/record/1227949/files/eHieee.png$$y00000 Total cross section for ionization of atomic hydrogen by low energy electrons. Experimental data (open circles) are from \cite{shah87}, the solid line isour simulation according to equation (\ref{sbeb}).
001227949 8564_ $$82434048$$s59732$$uhttp://cds.cern.ch/record/1227949/files/eC3H8ieee.png$$y00001 Total cross section for ionization of $C_3H_8$ by low energy electrons. Experimental data (open circles) are from \cite{grill93}, the solid line is our simulation according to equation (\ref{sbeb}). The propane molecular parameters used in the simulation were parameterized in~\cite{hkr95}.
001227949 916__ $$sn$$w200949
001227949 960__ $$a11
001227949 961__ $$c20100408$$h1737$$lCER01$$x20091210
001227949 963__ $$aPUBLIC
001227949 962__ $$b1166347$$norlando20091025
001227949 970__ $$a002863427CER
001227949 980__ $$aPREPRINT
001227949 980__ $$aConferencePaper